the highest of highs for someone and the lowest of lows. manic episodes charactered by things you might expect. overly euphoric feelings and jumpy, agitated behavior, pushed or racing speech and impulsive behavior are some of the characters people have an episode of mania and that sort of makes people think about the possibility is this actually part of bipolar have they have the lowest of lows and depressive episodes, these sorts of characteristics. loss of interest in things you find fun. what is amazing to me this idea now, new research coming out sort of looking at the fact that people's brains could be different someone, for example, going through a manic episode. i think this is fascinating. on the left here is sort of what a normal brain looks like. you see the activity on this functional mri. this is the frontal lobe and think of that as the filter. you think about something before you say it, you think about something before you do it. that is regulated over here. now look at the brain of someone in a manic episode. there is hardly any activity