'SHAMELESS' Series Finale Post - After Party + How did it end?! New Series Finale stills: TONIGHT IS THE NIGHT. Here's a look at the LAST new episode of #Shameless ever. �� pic.twitter.com/VZgRG6CbQV— Shameless on Showtime (@SHO_Shameless) April 11, 2021 Also, they'll be hosting a live after party with the cast: [ The episode is already available for digital subscribers, so how did the show end? [ Frank does not die from the last episode's overdose, but his dementia makes him walk confused on the streets, a woman tells him to wear a mask and he picks up a mask from the floor. He ends up in the hospital and is positive for COVID-19.