JPMorgan Is Americaâs Largest Company In 2021, But Amazon Is Rising In The Ranks Share to Facebook Share to Linkedin Through a pandemic that sparked an economic recession and financial volatility, Americaâs 10 largest companies kept getting bigger by every conceivable metric. Forbes Global 2000 list ranks the worldâs largest public companies with composite scores of market value, sales, profits and assets captured during the 12 months ended April 16. For the biggest companies in the United States, all those statistics have grown larger. Americaâs top 10 public companies recorded combined sales exceeding $2.2 trillion (up 29% from last year), profits of more than $316 billion (up 17%), and assets greater than $13.2 trillion (up 5%). Their combined market value also ballooned 87% over the past year to roughly $9.6 trillion.