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Landmark opioid trial reaches conclusion as closing arguments wrap


Paul T. Farrell Jr., an attorney representing plaintiffs in a lawsuit against three major U.S. drug distributors, speaks to reporters Wednesday, July 28, 2021, outside the federal courthouse in Charleston. Attorneys finished giving closing arguments in the case brought by Cabell County and the city of Huntington accusing AmerisourceBergen, Cardinal Health and McKesson of creating a public nuisance by distributing 81 million pills over eight years.
John Raby | The Associated Press ....

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Doctors blast Biogen Alzheimer approval as 'regulatory failure'


Jul 29, 2021
Top researchers who advised the U.S. Food and Drug Administration on Biogen Inc.’s Alzheimer’s drug blasted the agency for approving it, calling the decision a “regulatory failure” that is “at odds with the evidence.”
The New England Journal of Medicine opinion piece, signed by seven members of an advisory panel that opposed clearing Biogen’s Aduhelm, is another sign of persistent furor over the agency’s decision. Two committees of the House of Representatives investigating the approval have asked the Cambridge, Massachusetts-based biotech to turn over documents about the drug’s development and approval.
Doctors and patients are desperate for new treatments for Alzheimer’s disease, which afflicts more than 5 million Americans. While many researchers have backed the FDA’s move, the drug hasn’t been shown to slow cognitive decline, as two big trials sponsored by Biogen yielded contradictory results. Three of the panel members ....

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