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Fighting harmful bacteria with nanoparticles

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IMAGE: Deadly contact: Researchers at Empa and ETH have developed nanoparticles (red) that can kill resistant bacteria (yellow).
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Credit: Empa
In the arms race mankind against bacteria , bacteria are currently ahead of us. Our former miracle weapons, antibiotics, are failing more and more frequently when germs use tricky maneuvers to protect themselves from the effects of these drugs. Some species even retreat into the inside of human cells, where they remain invisible to the immune system. These particularly dreaded pathogens include multi-resistant staphylococci (MRSA), which can cause life-threatening diseases such as sepsis or pneumonia.
In order to track down the germs in their hidouts and eliminate them, a team of researchers from Empa and ETH Zurich is now developing nanoparticles that use a completely different mode of action from conventional antibiotics: While antibiotics have difficulty in penetrating human cells, thes ....

Inge Herrmann , Tino Matter , Investigator Collection , Cell Biology , Medicine Health , Infectious Emerging Diseases , Biomedical Environmental Chemical Engineering ,

Handwashing responsible for bacteria in sinks, largest non-hospital study shows

Handwashing is shaping communities of bacteria that live and grow in the plumbing of domestic sinks, scientists have found. ....

Zoe Withey , University Of Reading , Hyun Soon Gweon , Ecology Environment , பல்கலைக்கழகம் ஆஃப் ரீடிஂக் ,

Probiotic Lactobacillus acidophilus shows promise for treating inflammatory bowel disease and other

Credit: Rana Al-Sadi, PhD
Philadelphia, April 20, 2021 - Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut. A defective intestinal TJ barrier, sometimes known as leaky gut, plays an important role in exacerbating and prolonging intestinal inflammation. New research reported in
L. acidophilus) strain known as LA1 can generate a rapid and sustained enhancement of this defective intestinal barrier and effectively treat intestinal inflammation by preserving and restoring the intestinal barrier.
The use of probiotics has emerged as a therapy for a number of intestinal disorders, including IBD and necrotizing enterocolitis; however, specific probiotic bacteria with true beneficial effects on intestinal disease need to be identified. In this study researchers used high-throughput screening to ass ....

United States , Hershey Medical Center , Thomas Ma , Penn State College Of Medicine , American Journal , Penn State College , Cell Biology , Medicine Health , Nutrition Nutrients , ஒன்றுபட்டது மாநிலங்களில் , ஹெர்ஷே மருத்துவ மையம் , தாமஸ் மா , பென் நிலை கல்லூரி ஆஃப் மருந்து , அமெரிக்கன் இதழ் , பென் நிலை கல்லூரி ,

Quality and quantity of enrichments influence well-being of aquaculture fishes

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IMAGE: The research demonstrates that stone enrichments that have been previously conditioned in lake water significantly improve survival of aquaculture fish compared to clean stones.
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Credit: Pekka Hyvärinen/Luke
Collaborative research of the University of Jyvaskyla and Natural Research Institute Finland presents new evidence of the effects of enriched rearing on well-being of aquaculture fishes. The research demonstrates that stone enrichments that have been previously conditioned in lake water significantly improve survival of fish compared to clean stones. Also a higher number of stones has a similar positive effect. The results have practical implications for prevention of aquaculture diseases. The study was published in ....

Keski Suomi , Pekka Hyv , Lotta Riina Sundberg , Anssi Karvonen , Natural Resources Institute Finland , University Of Jyvaskyla , Voimalohi Ltd , Natural Research Institute Finland , University Of Jyv , Senior Lecturer Anssi Karvonen , Natural Resources Institute , Riina Sundberg , Agricultural Production Economics , Fisheries Aquaculture , Marine Freshwater Biology , இயற்கை வளங்கள் நிறுவனம் பின்லாந்து , இயற்கை வளங்கள் நிறுவனம் ,

Superbug killer: New nanotech destroys bacteria and fungal cells

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IMAGE: A fungal cell (green) interacting with a nanothin layer of black phosphorous (red). Image magnified 25,000 times.
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Credit: RMIT University
Researchers have developed a new superbug-destroying coating that could be used on wound dressings and implants to prevent and treat potentially deadly bacterial and fungal infections.
The material is one of the thinnest antimicrobial coatings developed to date and is effective against a broad range of drug-resistant bacteria and fungal cells, while leaving human cells unharmed.
Antibiotic resistance is a major global health threat, causing at least 700,000 deaths a year. Without the development of new antibacterial therapies, the death toll could rise to 10 million people a year by 2050, equating to $US100 trillion in health care costs. ....

United States , Vi Khanh Truong , Aaron Elbourne , Michelle Spencer , Sruthi Kuriakose , Andrew Christofferson , Patrick Taylor , James Chapman , Sumeet Walia , Samuel Cheeseman , Russell Crawford , Nhiem Tran , School Of Engineering , Deakin University , Swinburne University Of Technology , School Of Science , American Chemical Society , Applied Materials , Postdoctoral Fellow , Associate Professor Sumeet Walia , Professor Russell Crawford , Professor Michelle Spencer , Microanalysis Facility , Swinburne University , Chemistry Physics Materials Sciences , Medicine Health ,