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Cutting edge technique uses fluctuations in video pixels to measure energy use of developing embryos

Scientists have made a major breakthrough in the study of embryonic development and how it can be impacted by external factors such as climate. ....

United Kingdom , United Kingdom Research , United Nation Sustainable Development Goal , Marine Sciences , University Of Plymouth , Oli Tills , Research Fellow , Future Leaders Fellowship , Artificial Intelligence , Big Data , Times Higher Education Impact Rankings , United Nations , Artificial Intelligence , Embryonic Development , Research Fellow , Computer Vision , Climate Change , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது கிஂக்டம் ஆராய்ச்சி , ஒன்றுபட்டது தேசம் நிலையான வளர்ச்சி இலக்கு , கடல் அறிவியல் , பல்கலைக்கழகம் ஆஃப் ப்லிமத் , ஆராய்ச்சி சக , எதிர்கால தலைவர்கள் கூட்டுறவு , செயற்கை உளவுத்துறை , பெரியது தகவல்கள் ,

Modeling can predict mutation

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IMAGE: Computational modeling shows that mutations on SARS-CoV-2 s spike protein that enhance the virus ability to bind to the ACE2 receptor occur in two clusters or mutation hotspots.
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Credit: Image courtesy of Hin Hark Gan and Kristin Gunsalus, NYU s Department of Biology
SARS-CoV-2 has evolved to acquire mutations on the spike protein the part of the virus that protrudes from its surface and latches onto cells to infect them that enhance the coronavirus ability to bind to human cells or evade antibodies. A new study from the Centers for Genomics and Systems Biology at New York University and NYU Abu Dhabi uses computational modeling to assess the biological significance of spike protein mutations, uncovering versions of the virus that bind more tightly or resist antibodies and offering a promising public health surveillance tool. ....

South Africa , Abu Dhabi , Abuz Aby , United Arab Emirates , Benoit Marchand , Kristinc Gunsalus , Centers For Genomics , Systems Biology At New York University , Abu Dhabi High Performance Computing Group , Systems Biology , New York University , Molecular Biology , Hin Hark Gan , Alan Twaddle , High Performance Computing , Algorithms Models , Medicine Health , Infectious Emerging Diseases , Public Health , Technology Engineering Computer Science , ஒன்றுபட்டது அரபு அமீரகங்கள் , பெனாய்ட் மார்ச்சண்ட் , அமைப்புகள் உயிரியல் இல் புதியது யார்க் பல்கலைக்கழகம் , அமைப்புகள் உயிரியல் , புதியது யார்க் பல்கலைக்கழகம் , மூலக்கூறு உயிரியல் ,

Computer-Based Modeling Can Predict Mutation "Hotspots" and Antibody Escapers in SARS-CoV-2 Spike Protein

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Computer-Based Modeling Can Predict Mutation “Hotspots” and Antibody Escapers in SARS-CoV-2 Spike Protein
Study Identifies Structural Basis of Spike Protein Mutations with Stronger Binding and Antibody Resistance, Which May Explain Transmissibility of New COVID-19 Variants
Computational modeling shows that mutations on SARS-CoV-2’s spike protein that enhance the virus’ ability to bind to the ACE2 receptor occur in two clusters or mutation “hotspots.” Image courtesy of Hin Hark Gan and Kristin Gunsalus, NYU’s Department of Biology
SARS-CoV-2 has evolved to acquire mutations on the spike protein-the part of the virus that protrudes from its surface and latches onto cells to infect them-that enhance the coronavirus’ ability to bind to human cells or evade antibodies. A new study from the Centers for Genomics and Systems Biology at New York University and NYU Abu Dhabi uses computational modeling to assess the biological significance of spi ....

South Africa , Abu Dhabi , Abuz Aby , United Arab Emirates , Benoit Marchand , Kristinc Gunsalus , Kristin Gunsalus , Centers For Genomics , Systems Biology At New York University , Abu Dhabi High Performance Computing Group , Department Of Biology , Study Identifies Structural Basis , Spike Protein Mutations , Stronger Binding , Antibody Resistance , Which May Explain Transmissibility , Hin Hark Gan , Systems Biology , New York University , Molecular Biology , Alan Twaddle , High Performance Computing , South Africa , Abu Dhabi , New York , Molecular Biology ,

Long search finds grain of hope in the glume

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IMAGE: On the left is an isogenic line of UK spring wheat, Paragon, with the inclusion of the Polish wheat gene VRT-A2. It is 99% similar to Uk spring wheat.
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Credit: John Innes Centre
Researchers have found the elusive genetic element controlling the elongated grains and glumes of a wheat variety identified by the renowned botanist Carl Linnaeus more than 250 years ago.
The findings relating to Polish wheat, Triticum polonicum, could translate into genetic improvements and productivity in the field.
Wheat, in bread, pasta, and other forms, is a vital energy and protein source for humans. Each individual grain is nestled within the glumes and other leaf-like organs called lemma and palea which affect the grain s final size, shape, and weight. ....

United Kingdom , Carl Linnaeus , Cristobal Uauy , Nikolai Adamski , John Innes Centre , Agricultural Production Economics , Ood Food Science , Plant Sciences , Biomechanics Biophysics , ஒன்றுபட்டது கிஂக்டம் , ஜான் இநெஸ் மையம் ,

How can we prepare for future pandemics?

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How can we prepare for future pandemics?
EMBL and Portugal gather leading international experts to showcase progress in the fight against COVID-19 and share lessons for the future
Thousands of participants from across the globe came together to engage with leading figures from healthcare, academia, and industry. Credit: Holly Joynes/EMBL
On 27 April, participants from more than 100 countries gathered to discuss key lessons from the COVID-19 pandemic. As part of an enterprise implemented by Portugal during its presidency of the Council of the EU, EMBL and Portugal brought international experts together for a virtual conference. A wide range of topics were covered, including immunology, infectious diseases, and the molecular biology of viruses. The conference provided a valuable opportunity to ensure that important lessons are not lost in the rush towards a world where life is no longer so dominated by COVID-19. ....

Institut Pasteur , Dominique Costagliola , Ewan Birney , Sylvie Briand , Jeremy Farrar , Edith Heard , Holly Joynes , Etienne Simon Loriere , Nevan Krogan , Nassos Typas , European Bioinformatics Institute , Group Leader , Quantitative Biosciences Institute , University Of California San Francisco , Emerging Infectious Disease , General Edith , California San Francisco , Senior Scientist Nassos Typas , Senior Scientific Director , Bacterial Vaccines , Chief Medical Officer , Wellcome Trust , Global Infectious Hazard Preparedness , Deputy Director , Director General , Bioinformatics Institute ,