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Two Danforth Center scientists receive prestigious awards

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ST. LOUIS, MO, March 11, 2021 - Two Danforth Center Principal Investigators were recently recognized with early career awards for outstanding achievement and leadership.
Andrea Eveland, Ph.D., associate member, received the Marcus Rhoades Early Career Award at the 63rd Maize Genetics Conference (MGC) for her research that mixes genomics, developmental biology, and advanced bioinformatics. The MGC Marcus Rhoades Early Career award recognizes an individual who has made significant research contributions through genetic studies of maize or related species, and has been in a permanent position for eight or fewer years.
Eveland has been an active member of the MGC community for 18 years, the last six of which have been at the Danforth Center. Her research is focused on genetic control of plant architecture and regulation of abiotic stress response. Eveland leads a $3.4M National Science Foundation-funded project that leverages developmental biology, genomics, and ....

Malia Gehan , Andrea Eveland , Jim Carrington , J Gary Tallman , Plant Biology At Michigan State University , International Plant Phenotyping Network , American Plant Phenotyping Network , University Of Florida , Pm National Science , Cold Spring Harbor Laboratory , Danforth Center Principal Investigators , Postdoctoral Research Scientist , Danforth Center , Biology At Willamette University , Maker Group , Marcus Rhoades Early Career Award , Maize Genetics Conference , Rhoades Early Career , National Science Foundation Funded , Early Career Award , Career Award , Principal Investigator , Plant Biology , Michigan State University , Willamette University , Cell Biology ,

NIH researchers develop guidelines for reporting polygenic risk scores

Scientists and healthcare providers are beginning to use a new approach for assessing a person's inherited risk for diseases like Type 2 diabetes,. ....

United Kingdom , United States , Genevieve Wojcik , Erin Ramos , Katrina Goddard , Michael Inouye , Division Of Genomic Medicine , Health Data Research , Division Of Intramural Research , Human Services , National Institutes Of Health , Cambridge Baker Systems Genomics Initiative , Diabetes Institute , Kaiser Permanente Center , University Of Cambridge , European Bioinformatics Institute , Department Of Health , Johns Hopkins Bloomberg School Of Public Health , National Human Genome Research Institute , Health Research , Stanford University , Genome Resource , Complex Disease Working Group , Polygenic Score Catalog , National Institutes , Genomic Medicine ,

Scientists bring polygenic risk scores closer to clinical use

Researchers have established the first universal reporting standards and open access platform for polygenic risk scores, paving the way for widespread. ....

United Kingdom , Michael Inouye , Baker Institute , Diabetes Institute , Baker Institute Munz , University Of Cambridge , European Bioinformatics Institute , Health Data Research United Kingdom , Baker Institute Public , Us National Institutes Of Health , Stanford University , Baker Heart , Polygenic Risk Score Reporting Statement , Nature Genetics , Bioinformatics Institute , Health Data Research United , Munz Chair , Cardiovascular Prediction , Prevention Professor Michael Inouye , Coronary Artery Disease , Polygenic Risk Score , Genetic Testing , Heart Disease , ஒன்றுபட்டது கிஂக்டம் , மைக்கேல் இணௌஉயே , ரொட்டி சுடுபவர் நிறுவனம் ,

SARS-CoV-2 UK variant could soon be dominant in Switzerland

Researchers at the Swiss Institute of Bioinformatics estimate that the B.1.1.7 variant may be dominant in Switzerland by March. ....

United States , South Africa , United Kingdom , South African , Angela Betsaidab Laguipo , Swiss Institute Of Bioinformatics , World Health Organization , Angela Betsaida , Swiss Institute , Image Credit , Coronavirus Disease Covid 19 , Genomic Sequencing , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , சுவிஸ் நிறுவனம் ஆஃப் உயிர் தகவலியல் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , சுவிஸ் நிறுவனம் , படம் கடன் , உயிர் தகவலியல் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

The 3Rs of the genome: Reading, writing, and regulating

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IMAGE: Researchers have precisely mapped the binding locations of over 400 proteins on the yeast genome using ChIP-exo. The method (top) uses an antibody to fish out a specific DNA-bound protein.
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Credit: Pugh Lab, Cornell and Mahony Lab, Penn State
A massive effort to map the precise binding locations of over 400 different kinds of proteins on the yeast genome has produced the most thorough and high-resolution map of chromosome architecture and gene regulation to date. The study reveals two distinct gene regulatory architectures, expanding the traditional model of gene regulation. So-called constitutive genes, those that perform basic housekeeping functions and are nearly always active at low levels require only a basic set of regulatory controls; whereas those that that are activated by environmental signals, known as inducible genes, have a more specialized architecture. This finding in yeast could open the door to a better unders ....

Prashantk Kuntala , Nitika Badjatia , Ninap Farrell , Katelyns Mistretta , Joshuad Mairose , Matthewj Rossi , Grettad Kellogg , Kylie Bocklund , Thomasr Blanda , Naomi Yamada , Emilys Perkinson , Chitvan Mittal , Shaun Mahony , Davidj Rocco , Williamkm Lai , B Franklin Pugh , Penn State Institute For Computational , Us National Institutes Of Health , Data Sciences , Cornell University , Us National Science Foundation , Penn State , Guray Kuzu , Science Foundation , Penn State Institute , Advanced Cyberinfrastructure ,