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The Mediterranean diet (MedDiet) has been associated with cognitive performance. Yet, controlled trials have yielded contradictory results. To tackle this controversy, a comprehensive multimodal analysis of the association of the MedDiet with cognitive performance and brain structure in normative aging is still necessary. To address this issue, community-dwellers ≥50 years from a cohort study on normative aging (n=76) underwent a i) magnetic resonance imaging session with two acquisitions: structural and Diffusion-Weighted Imaging; ii) neuropsychological battery of tests focusing on memory a...

Background: Saudi Arabia, a prominent Arabian country, has 35.3 million persons living in 2.2 million square kilometers, undergone serious threats, recently, due to the COVID-19 pandemic. With the built in infrastructure and disciplined life, the country could address this pandemic. Aims: This analysis of COVID-19 cases in Saudi Arabia, attempts to assess the situation, explore its global percentage share, percentage of population affected, and local distribution from the beginning of infection till recently, tracing historical developments and changes. Data and methods: This analysis made use...

The Paris Agreement’s decentralized and bottom-up approach to climate action poses an enormous accounting challenge by substantially increasing the number of heterogeneous national, sub-national, and non-state actors. Current legacy climate accounting systems and mechanisms are insufficient to avoid information asymmetry and double-counting due to actor heterogeneity and fragmentation. This paper presents a nested climate accounting architecture that integrates several innovative digital technologies, such as Distributed Ledger Technology, Internet of Things, machine learning, and concepts s...

On 13 July 2004, during an expedition exploring biodiversity along the northern Mid-Atlantic Ridge, an ROV dive recorded videos of numerous sublinear sets of holes in sediment at ca. 2082 m depth. The location was north of the Azores. Each set appeared track-like. Lengths of individual series ranged from <1 m to many meters. Each was straight or gently curved. Some series intersected or crossed. Close examination of the holes showed them to be elongate, with the long axis parallel to the axis of the series. The holes were ca. 6 x 1.5 cm, with distance between holes similar to hole length. T...

Breast cancer affects more than one million women per year worldwide. Through this study, we develop a nanoparticle-based drug delivery system to target breast cancer cells. Aspirin has been found to inhibit thromboembolic diseases with its tumor-preventing activity. As a consequence, it relieves disease symptoms and severity. Here, mesoporous Silica Nanoparticles (MNP) have been used to deliver Aspirin to the tumor location. MNP-based Aspirin in folic acid (F)-conjugated Polydopamine (MNP-Asp-PD-PG-F) vehicles are prepared for targeted breast cancer therapy. The vehicle hinges on MNP altered ...