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A recent study in Science Advances found that early-life tobacco exposure, including in-utero and early smoking initiation, accelerates biological aging, emphasizing the importance of reducing exposure to improve health outcomes.
Genomics plc and GSK announced a new collaboration to explore the potential for using polygenic risk scores (PRS) in clinical trials, to improve understanding of disease risk and patient selection, which could support optimization of trial design.
Omega-6 fatty acids, commonly found in eggs, poultry, and seafood, could reduce the risk of bipolar disorder, according to a world-first study from the University of South Australia.
Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.
Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.
Probiotics offer a range of health benefits, but their adverse effects can occasionally lead to bacteremia, wherein bacteria circulate in the bloodstream throughout the body.
Study shows that disruptions in the gut microbiota of male mice can negatively affect offspring health, leading to growth issues and increased mortality. However, restoring the father's microbiota before conception may prevent these problems.