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VEXAS syndrome in men is more common than previously thought

VEXAS syndrome in men is more common than previously thought
A rare disease first identified in 2020 is much more common than first thought, say researchers at the University of Leeds investigating its origins.
VEXAS syndrome is a serious inflammatory condition which develops in men over 50, causing them to become very sick and fatigued, and can be fatal. It was originally thought to be rare, but a new study has identified genetic mutations which indicate that the disease is actually much more common.
The researchers developed a genetic test to identify patients who may have the disease, and now want to screen more people showing symptoms to understand exactly how common it is. ....

United Kingdom , Sinisa Savic , James Poulter , Emily Henderson , School Of Medicine , European Reference Network , University Of Leed School Medicine , University Of Leeds , Clinical Associate Professor , Leed School , Honorary Consultant , Leeds Teaching Hospitals , Academic Fellow , Molecular Neuroscience , Clinical Immunology , Bone Marrow , Rare Disease , Sex Chromosome , ஒன்றுபட்டது கிஂக்டம் , எமிலி ஹென்டர்சன் , பள்ளி ஆஃப் மருந்து , ஐரோப்பிய குறிப்பு வலைப்பின்னல் , பல்கலைக்கழகம் ஆஃப் லீட் பள்ளி மருந்து , பல்கலைக்கழகம் ஆஃப் லீட்ஸ் , மருத்துவ இணை ப்ரொஃபெஸர் , லீட் பள்ளி ,

Study uncovers 50 new genes for eye color

Study uncovers 50 new genes for eye color
The genetics of human eye color is much more complex than previously thought, according to a new study published today.
An international team of researchers led by King s College London and Erasmus University Medical Center Rotterdam have identified 50 new genes for eye color in the largest genetic study of its kind to date. The study, published today in
Science Advances, involved the genetic analysis of almost 195,000 people across Europe and Asia.
These findings will help to improve the understanding of eye diseases such as pigmentary glaucoma and ocular albinism, where eye pigment levels play a role. ....

City Of , United Kingdom , Manfred Kayser , Pirro Hysi , Emily Henderson , King College London , Erasmus University Medical Center Rotterdam , College London , Science Advances , Co Senior Author , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , ம்யாந்ஃப்ரெட் கய்சேர் , எமிலி ஹென்டர்சன் , கிங் கல்லூரி லண்டன் , ஈராஸ்மஸ் பல்கலைக்கழகம் மருத்துவ மையம் ரோட்டர்டாம் , கல்லூரி லண்டன் , இணை மூத்தவர் நூலாசிரியர் ,

Could an "ACE2 Triple Decoy" be an alternative approach to neutralizing SARS-CoV-2?

A team of scientists from the USA recently developed a recombinant “Angiotensin converting enzyme 2 (ACE2) Triple Decoy” that can trap SARS-CoV-2 and prevent its propagation inside the host cell. ....

United States , Sanchari Sinha Dutta , Image Credit , Coronavirus Disease Covid 19 , Sars Cov 2 , Binding Affinity , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , சஞ்சரி சீன்ஹா தத்தா , படம் கடன் , பிணைப்பு இன உறவு , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders
A team of researchers from the Agency for Science, Technology and Research s (A STAR) Genome Institute of Singapore (GIS) have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders. Their research was published in
Nature Communications on 2 March 2021.
One in seventeen people in the world suffers from some type of genetic disorder. Chances are, you or someone you know - a relative, friend, or colleague - is one of approximately 450 million people affected worldwide. Mutations responsible for these disorders can be caused by multiple mutagens - from sunlight to spontaneous errors in your cells. The most common mutation by far is the single-based substitution, in which a single-base in the DNA (such as G) is replaced by another base (such as C). Countless cystic fibrosis patients worldwide have C instead of G, leading to ....

Kwei Leong , Emily Henderson , Agency For Science , Genome Institute Of Singapore , Nature Communications , Senior Research Scientist , Genome Institute , C Tog Base Editor , Chew Wei Leong , Young Scientist Award , Patrick Tan , Executive Director , Cystic Fibrosis , Genetic Disorder , வெய் லியோங் , எமிலி ஹென்டர்சன் , மரபணு நிறுவனம் ஆஃப் சிங்கப்பூர் , இயற்கை தகவல்தொடர்புகள் , மூத்தவர் ஆராய்ச்சி விஞ்ஞானி , மரபணு நிறுவனம் , மெல் வெய் லியோங் , இளம் விஞ்ஞானி விருது , பேட்ரிக் பழுப்பு , நிர்வாகி இயக்குனர் , சிஸ்டிக் ஃபைப்ரோஸிஸ் , ஜெநெடிக் கோளாறு ,

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials
Henry Ford Cancer Institute is launching the Participatory Action for Access to Clinical Trials (PAACT) project to dramatically improve the representation of the African American community and other minorities in cancer clinical trials.
Supported by a $750,000 grant from Genentech, PAACT is a community-based research initiative in collaboration with the Detroit Community-Academic Urban Research Center (Detroit URC) that will address various barriers to trust and participation in clinical trials. Researchers and community partners will focus on clinical trials involving breast, colorectal, lung, and prostate cancers, which are more likely to result in death for African Americans when compared to other racial and ethnic groups. The project is being implemented in partnership with community-based organizations and community leaders who are key stakeholders. ....

United States , Grace Community Church , Mary Waters , Eleanorm Walker , Sophia Chue , Donnam Harris , Emily Henderson , Parkside Zachary Rowe , Evelyn Jiagge , Henry Ford , Benjamin Movsas , Eastside Community Network Jillian Dewitt , Integrative Services , Academic Urban Research Center Detroit , Institute For Population Health Gwendolyn Daniels , Community Advocacy , Henry Ford Cancer Institute , Ghana Association , Neighborhood Service Organization Linda Little , Um School Of Nursing , Steering Committee , Detroit Community , Caribbean Community Service Center , Henry Ford Breast Cancer Research , Um School Of Public Health , Ford Cancer Institute ,