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SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers
Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.
The team’s molecular surveillance study, which included samples from more than 3,000 patients, detected SARS-CoV-2 RNA in specimens collected during the week ending 25
th January.
The samples were respiratory pathogen-negative (RPN)-specimens taken from patients being evaluated for flu-like illness and respiratory symptoms during the first ten weeks of 2020. ....

New York , United States , Emilia Sordillo , Sally Robertson , Mount Sinai Health System , Icahn School , Mount Sinai , New York City , Molecular Evidence , New York City Prior , Image Credit , North America , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Respiratory Illness , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , சாலி ராபர்ட்சன் , ஏற்ற சினை ஆரோக்கியம் அமைப்பு , இக்ஹ்ன் பள்ளி , ஏற்ற சினை , புதியது யார்க் நகரம் , மூலக்கூறு ஆதாரம் ,

Scientists Create Fully Functioning Neanderthal Mini Brain

Brain Development And The Neanderthal Mini-brain
The complete genome of the Neanderthal species was sequenced in 2013, from a phalanx (finger bone) Neanderthal fossil found in Siberia.
With this information in hand, the UC San Diego School of Medicine research team sought to isolate Neanderthal genes that were intimately involved in brain development processes. They eventually settled on NOVA1 as a candidate worth studying, and then set about designing an experiment that would prove their hypothesis that NOVA1 had a meaningful impact.
Using the characteristics of NOVA1’s genetic fingerprint as their guide, the researchers applied CRISPR gene-editing technology to malleable stem cells, in order to replicate Neanderthal brain cells in controlled laboratory conditions. ....

United States , San Diego , Stefan Scheer , Alysson Muotri , Daniela Hitzemann , Brain Development , Cellular Medicine At University Of California , Muotri Lab , Uc San Diego School Of Medicine , Diego School , Cellular Medicine , Your Brain , Mini Brain , Stem Cells , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , ஸ்டீபன் ஸ்கீயர் , மூளை வளர்ச்சி , செல்லுலார் மருந்து இல் பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , அக் சான் டியாகோ பள்ளி ஆஃப் மருந்து , டியாகோ பள்ளி , செல்லுலார் மருந்து , உங்கள் மூளை , மினி மூளை , தண்டு செல்கள் ,

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater
As new variants emerge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen causing the current coronavirus disease 2019 (COVID-19) pandemic, continue to circulate, early identification and sequencing have become a necessary part of research in this area. This virus is known to be shed from the nose, the lungs, the saliva, urine, and feces.
A new study, published on the
medRxiv preprint server, reports the use of metagenomics to detect the virus from wastewater samples, indicating community-level circulating variants that are not yet identified or are present in very low proportions on clinical databases. ....

Liji Thomas , Wastewater By High Throughput , Image Credit , People Image Studio , Wastewater Based Epidemiology , Coronavirus Disease Covid 19 , High Throughput Sequencing , Sars Cov 2 , Amino Acid , Corona Virus , Genomic Sequencing , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , படம் கடன் , மக்கள் படம் ஸ்டுடியோ , கழிவு நீர் அடிப்படையிலானது தொற்றுநோய் , அமினோ அமிலம் , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

LifeArc supports the GenOMICC COVID-19 Study

LifeArc supports the GenOMICC COVID-19 Study
Medical research charity, LifeArc, announces today that it is providing £5 million funding to support the work of the GenOMICC COVID-19 Study, led by the GenOMICC consortium in partnership with Genomics England. The study, launched in May 2020, is using genomics to investigate why some people are affected more severely by COVID-19, and increase our understanding about the disease.
GenOMICC is a global collaboration of doctors and scientists working together to understand and treat serious illnesses, including emerging infections like SARS, MERS and now COVID-19. The partnership with Genomics England was formed to enable large scale and rapid whole genome sequencing and analysis for NHS COVID-19 patients, leveraging Genomics England s sequencing and analysis ecosystem available to researchers. ....

United Kingdom , City Of , Melanie Lee , Chris Wigley , Kenneth Baillie , Emily Henderson , University Of Edinburgh , United Kingdom Department Of Health , Genomics England , United Kingdom Department , Social Care , Chief Executive Officer , Chief Investigator , Academic Consultant , Critical Care Medicine , Medical Research , Whole Genome Sequencing , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , மெலனி லீ , கிறிஸ் விக்லி , கெநெத் பெய்லி , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் எடின்பர்க் , ஒன்றுபட்டது கிஂக்டம் துறை ஆஃப் ஆரோக்கியம் , மரபியல் இங்கிலாந்து ,

SARS-CoV-2's resistance to remdesivir in vitro

SARS-CoV-2 s resistance to remdesivir in vitro
With over 108 million reported infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide, and nearly 2.4 million deaths, the ongoing pandemic has jeopardized the physical, financial and emotional wellbeing of the global population over the past year. A new preprint research paper posted to the
bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.
In an effort to arrest the spread of SARS-CoV-2 infection, drug development and repurposing research has been proceeding at a rapid pace in multiple centers. ....

South Africa , United Kingdom , South African , Liji Thomas , World Health Organization , Solidarity Therapeutics Trial , In Vitro , Sars Cov 2 , Amino Acid , Anti Inflammatory , Antiviral Drug , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது கிஂக்டம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , ஒற்றுமை சிகிச்சை சோதனை , இல் விட்ரோ , அமினோ அமிலம் , எதிர்ப்பு அழற்சி , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,