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Researchers to create computational models to improve treatments for ovarian cancer


Researchers to create computational models to improve treatments for ovarian cancer
The 5-year research project involves 14 organizations in seven EU countries and is funded by €15 M from the EU.
The Genome Data Science lab, led by ICREA researcher Fran Supek, will analyze the evolution of ovarian tumors to develop computational models for predicting treatment resistance.
The EU has granted €15 M to fund a 5-year project that seeks to improve personalized treatments for ovarian cancer. The international DECIDER project involves partners from 14 organizations in seven EU countries.
In Europe, over 40000 women die of ovarian cancer every year. In addition to surgery, most patients are treated with platinum-based chemotherapy. Unfortunately, the effect of the chemotherapy often decreases with treatment cycles, and few effective treatments are currently available for patients who develop resistance to platinum-based drugs. ....

Comunidad Autonoma De Cataluna , Eteläuomen Läi , Sampsa Hautaniemi , Fran Supek , Emily Henderson , University Of Helsinki , Genome Data Science , Ovarian Cancer , Research Project , காமுனிடட தன்னாட்சி டி கடலுள் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஹெல்சின்கி , மரபணு தகவல்கள் அறிவியல் , ஓவாயரியந் புற்றுநோய் , ஆராய்ச்சி ப்ராஜெக்ட் , அறுவை சிகிச்சை ,

Evolutionary history reveals the function of fish and human bitter receptors


Evolutionary history reveals the function of fish and human bitter receptors
To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients. These include receptors for bitter compounds, which first evolved during evolution in bony fishes such as the coelacanth.
What 400 million years of evolutionary history reveal about the function of both fish and human bitter receptors was recently published in the journal
Genome Biology and Evolution by a team of researchers led by the Leibniz Institute for Food Systems Biology at the Technical University of Munich and the University of Cologne. ....

Sigrun Korsching , Maik Behrens , Emily Henderson , Technical University Of Munich , University Of Cologne , Leibniz Institute , Leibniz Institute For Food Systems Biology , Genome Biology , Food Systems Biology , Technical University , Antonella Di Pizio , எமிலி ஹென்டர்சன் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , பல்கலைக்கழகம் ஆஃப் கொலோன் , மரபணு உயிரியல் , உணவு அமைப்புகள் உயிரியல் , தொழில்நுட்ப பல்கலைக்கழகம் ,

Scientists study how different genes dance to the circadian rhythm


Scientists study how different genes dance to the circadian rhythm
In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the wake-sleep cycle. To carry out their work, the scientists used the common fruit fly
Drosophila melanogaster, making this the sixth Nobel to be awarded to research involving it.
Fruitful fruit flies
Life scientists have been using
Drosophila for over a century now. First proposed by entomologist Charles W. Woodworth as a model organism, its use in research was pioneered by geneticist Thomas H. Morgan who ran his famous Fly Room at Columbia University in the early 1900 s. ....

Bart Deplancke , Maria Litovchenko , Charlesw Woodworth , Emily Henderson , Thomash Morgan , School Of Life Sciences , Drosophila Genetic Reference Panel , Fly Room At Columbia University , Nobel Prize , Fly Room , Columbia University , Life Sciences , Circadian Rhythm , Gene Expression , எமிலி ஹென்டர்சன் , தோமாஷ் மோர்கன் , பள்ளி ஆஃப் வாழ்க்கை அறிவியல் , ஈ அறை இல் கொலம்பியா பல்கலைக்கழகம் , நோபல் ப்ரைஸ் , ஈ அறை , கொலம்பியா பல்கலைக்கழகம் , வாழ்க்கை அறிவியல் , சர்க்காடியன் தாளம் , கீந் வெளிப்பாடு ,