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Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.

China , Chao-ma , Gorodenkoff-shutterstock , Society-for-laboratory-automation , National-scholarship-for-graduate-students-award , National-scholarship-for-encouragement-award , Company-of-biologists , Af-university , Cancer-research-institute , Research-assistant-professor , Ministry-of-education , College-of-innovation

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

China , Xianqun , Qinghai , Shanghai , David-liu , Xianqun-fan-department-of-ophthalmology , Science-china , Xianqun-fan , Shanghai-jiao-tong-university-school , Medicine-affiliated-ninth-people , Cas9 , Na

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

Wuhan , Hubei , China , Nature-reviews-drug-discovery , Drugs , Fficacy , Edicine , Lood , Ell , Oronavirus , Ovid-19

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it's hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

Italy , Italian , Istituto-clinico-humanitas , Marco-rasponi , Guido-torzilli , Biomimetic-microsystems , Humanitas-university , Italian-foundation-for-cancer-research , Hepatobiliary-immunopathology-laboratory-at-humanitas-research-hospital , Laboratory-of-microfluidics , Ana-lleo-de-nalda , Hepatobiliary-immunopathology-laboratory

Sweetener 'Stevia' does not alter gut microbiota composition, confirms new study

The impact of 12 weeks of regular consumption of stevia, non-nutritive sweeteners (NNSs), on the human gut microbiota.

Tatianamishina-shutterstock , Non-nutritive-sweetener-stevia , Does-not-alter , Human-gut , Image-credit , Principle-coordinates-analysis , Clostridium , Iabetes , Lucose , Lucose-metabolism , N-vitro

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

Sussex , East-sussex , United-kingdom , Chris-parris , Fiona-dempsey , Dr-hussein-al-ali-at-anglia-ruskin-university , Anglia-ruskin-university , Sussex-medical-school , Professor-chris-parris , Professor-chris-pepper , Life-sciences , Scientific-operations

Unlocking the anti-inflammatory secrets of bergamot byproducts

The positive effect of bergamot derivatives.

Italy , Chantarat-shutterstock , Bergamot-byproducts , Sustainable-source , Image-credit , Anti-inflammatory , Lzheimer-39s-disease , Sthma , Ancer , Hronic , Ytokine

Hundreds of chemicals linked to breast cancer risk identified in new study

Study identifies 921 chemicals potentially linked to breast cancer risk, using a framework evaluating genotoxicity and endocrine activity.

United-states , Us-environmental-protection-agency , Environmental-health-perspectives , International-agency-for-research-on-cancer , Key-characteristics-framework , Image-credit , International-agency , Protection-agency , Carcinogen , Reast-cancer , Ancer

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

Athens , Attikír , Greece , Emory-university , Georgia , United-states , University-of-georgia , Atlanta , Georgia-institute-of-technology , America , Hanjoong-jo , Robbie-cross-jr

Promising PET scanner tool developed for rare medullary thyroid cancer

A newly developed PET imaging agent has been found to be effective in identifying medullary thyroid cancer (MTC) in preclinical and clinical studies, according to research published in the January issue of The Journal of Nuclear Medicine.

Stanford-university , California , United-states , Germany , Constantin-lapa , University-hospital-augsburg , Stanford-university-in , Journal-of-nuclear-medicine , Society-of-nuclear-medicine , Nuclear-medicine , Cancer , Hyroid