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Omecamtiv Mecarbil brings greater benefits for severe heart failure

The experimental heart failure drug omecamtiv mecarbil reduced heart failure hospitalizations by a greater margin among patients with more severely reduced ejection fraction, a measure indicating severe impairment in the heart's pumping ability, compared with those who had moderately reduced ejection fraction, according to research presented at the American College of Cardiology's 70th Annual Scientific Session.

California , United-states , San-francisco , Johnr-teerlink , Nicole-napoli , Ann-nguyen , Omecamtiv-mecarbil , San-francisco-va-medical-center , University-of-california , Amgen , Cytokinetics-inc , Journal-of-the-american-college-cardiology

Rifapentine Polylactic Acid Microspheres for Spinal TB

*
1Department of Orthopeadics, The Affiliated Linfen Hospital of Shanxi Medical University, Linfen, Shanxi Province, People’s Republic of China;
2Department of Orthopeadics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, People’s Republic of China;
3Department of Orthopeadics, The Affiliated Shunde Hospital of Jinan University, Foshan, Guangdong Province, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xinghua Song
Department of Orthopeadics, The Affiliated Shunde Hospital of Jinan University, Foshan, 528303, People’s Republic of China
Zhen Wang
Department of Orthopeadics, The Affiliated Linfen Hospital of Shanxi Medical University, Linfen, 041000, People’s Republic of China

New-zealand , Xinjiang , Jiangxi , China , Chengdu , Sichuan , Grand-island , California , United-states , Japan , Tokyo , United-kingdom

New Method Holds Potential to Fight Botulinum Toxin

New Method Holds Potential to Fight Botulinum Toxin
by Angela Mohan on
January 7, 2021 at 3:23 PM
Science Translational Medicine by Patrick McNutt, PhD, of the Wake Forest Institute for Regenerative Medicine.
Furthermore, in a companion article, an independent team demonstrated that a related drug has robust efficacy in mice.
"This is one of those serendipitous moments in science where two groups, working independently, demonstrate similar results for a long-standing problem," McNutt said.
"We are currently modifying this drug to enhance its therapeutic properties against botulism and exploring whether the same approach can be repurposed to treat other neuronal diseases."
In 2010, Konstantin Ichtchenko (New York University School of Medicine) conceived of a novel 'trojan horse' strategy to treat botulism. This strategy is based on using a non-toxic form of BoNT to deliver therapeutic antibodies to paralyzed neurons, blocking wild-type toxin activity and accelerating recovery from paralysis.

Patrick-mcnutt , Wake-forest-institute-for-regenerative-medicine , Science-translational-medicine , Wake-forest-institute , Botulinum-toxin , Guinea-pigs , Rhesus-macaque-monkeys , Therapeutic-effect , Paralysis , Antibodies , பேட்ரிக்-ம்க்ணுத்த் , எழுந்திரு-காடு-நிறுவனம்-க்கு-மீளுருவாக்கம்-மருந்து

New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes

New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes
albuquerqueexpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from albuquerqueexpress.com Daily Mail and Mail on Sunday newspapers.

Langley , British-columbia , Canada , United-states , Ireland , Dublin , Canadian , Andrew-willoughby , Keithw-moeller , Andrewjm-willoughby , Allergan-plc , Verasil-therapeutic-research-inc

DGAP-News: New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes

DGAP-News: New W ...
DGAP-News: New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes
vom 16.12.2020, 13:00 Uhr
Bild: pixabay.com
DGAP-News:
/ Key word(s): Miscellaneous
New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes
16.12.2020 / 13:00
The issuer is solely responsible for the content of this announcement.
New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes
LANGLEY, BC / ACCESSWIRE / December 16, 2020 / Dr. Andrew J.M. Willoughby and Dr. Keith W. Moeller have been granted and issued numerous patents worldwide - including in Asia, Europe, and now the United States - on the combination and utilization of Nano-Silver with various Botulinum NeuroToxins ("BONTs"). These proprietary formulations have significant clinical and logistical advantages, including extending the stability and shelf-life of the reconstituted BONT from 2-3 weeks to upwards of 3-4 months, as well as extending the Therapeutic Effect (Efficacy) of the injected BONTs for up to 6-7 months (100+% longer than with standard saline).

Langley , British-columbia , Canada , United-states , Ireland , Dublin , Canadian , Andrew-willoughby , Keithw-moeller , Andrewjm-willoughby , Allergan-plc , Verasil-therapeutic-research-inc

New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes - Press Release

New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes - Press Release
digitaljournal.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from digitaljournal.com Daily Mail and Mail on Sunday newspapers.

Langley , British-columbia , Canada , United-states , Ireland , Dublin , Canadian , Andrew-willoughby , Keithw-moeller , Andrewjm-willoughby , Allergan-plc , Verasil-therapeutic-research-inc

VeraSIL Therapeutic Research, Inc.: New Worldwide Patents Issued on Discovery for Botulinum NeuroToxin in Combination with Silver Nano Particles Creating Extraordinary Outcomes

(1)
LANGLEY, BC / ACCESSWIRE / December 16, 2020 / Dr. Andrew J.M. Willoughby and Dr. Keith W. Moeller have been granted and issued numerous patents worldwide - including in Asia, Europe, and now the United States - on the combination and utilization of Nano-Silver with various Botulinum NeuroToxins ("BONTs"). These proprietary formulations have significant clinical and logistical advantages, including extending the stability and shelf-life of the reconstituted BONT from 2-3 weeks to upwards of 3-4 months, as well as extending the Therapeutic Effect (Efficacy) of the injected BONTs for up to 6-7 months (100+% longer than with standard saline).
Said Dr. Moeller,
"Because of the way this Nanoparticle is able to encapsulate and protect various proteins and carbohydrates from degradation, we believe the potential now exists that the Botulinum NeuroToxin may not need to be refrigerated at all, further extending its humanitarian use into more secluded nations and cities worldwide. Think of an adult or child that utilizes the BONT product to control chronic migraine headaches or recurrent focal motor seizures, who now may only need to be injected twice in a calendar year, instead of every 2-3 months. This discovery could impact the lives of many!"

Langley , British-columbia , Canada , United-states , Ireland , Dublin , Canadian , Andrew-willoughby , Kostenloser-wertpapierhandel , Keithw-moeller , Andrewjm-willoughby , Allergan-plc

DocFilm-20191027-12:16:00

sports are especially popular in bavaria and lower saxony in eastern germany the figure is significantly lower shooting was forbidden in the g.d. are. i'm visiting the xcel shooting club in hessen where 14 year old calin is training. with around 1400000 members the german shooting federation is one of the largest german sports associations kalin west stiff shooting closed to give her a more stable posture. unlike in switzerland young people here shoot only with air rifles. there's a special reason why catalin took up this hobby 2 years ago she was struggling with her concentration and her mother had the idea to register her with the rifle club she'd heard that shooting can have a therapeutic effect and boost attention span since then carolyn has been training

Shooting , Xcel-shooting-club , Eastern-germany , Figure , Old-calin , Lower-saxony , Gd- , Bavaria , Are , Hessen , 14 , Training

DocFilm-20191024-09:50:00

figure is significantly lower shooting was forbidden in the g.d. are. visiting the ect cell shooting club in hessen where 14 year old calin is training with around 1400000 members the german shooting federation is one of the largest german sports associations kalin where stiff shooting close to give her a more stable posture. unlike in switzerland young people here shoot only with the air rifles. there's a special reason why catalin took up this hobby 2 years ago she was struggling with her concentration and her mother had the idea to register with the rifle club she'd heard that shooting can have a therapeutic effect and boost attention span since then carolyn has been training at least twice a week the 2 hour session not only includes shooting but also progressive muscle

Training , Shooting , Members , Old-calin , Ect-cell-shooting-club , Figure , Shooting-federation , Gd- , Are , Hessen , 14 , One

DocFilm-20191023-05:50:00

figure is significantly lower shooting was forbidden in the g.d. r. i'm visiting the ect cell shooting club in hessen where 14 year old calin is training with around 1400000 members the german shooting federation is one of the largest german sports associations kalin where stiff shooting closed to give her a more stable posture. unlike in switzerland young people here shoot only with air rifles. there's a special reason why catalin took up this hobby 2 years ago she was struggling with her concentration and her mother had the idea to register with the rifle club she'd heard that shooting can have a therapeutic effect and boost attention span since then kalin has been training at least twice a week the 2 hour session not only includes shooting but also progressive muscle

Members , Shooting , Training , Old-calin , Ect-cell-shooting-club , Figure , Shooting-federation , Gdr- , Hessen , 14 , 1400000 , One