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Common mechanism found for diverse brain disorders: Study

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IMAGE: Jing-Qiong (Katty) Kang, M.D., Ph.D., associate professor of Neurology and Pharmacology, Vanderbilt University Medical Center.
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Credit: Vanderbilt University Medical Center
Researchers at Vanderbilt University Medical Center (VUMC) have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.
Their findings, reported last month in the journal
Brain, suggest that boosting transporter function via genetic or pharmacological means could be beneficial in treating brain disorders linked to these genetic variations.
This points (to) a clear direction of treating a wide spectrum of neurodevelopmental disorders, from various epilepsy syndromes (and) autism to neurodevelopmental delay and intellectual disabilities, caused by the pathological variants in this gene, sai ....

United States , Sarah Poliquin , Kathryn Rigsby , Gerald Nwosu , Wangzhen Shen , Alejandra Romero Morales , Vivian Gama , Anuj Rastogi , Jing Qiong Katty Kang , Felicia Mermer , Terry Jo Bichell , Innovation Fund , Researchers At Vanderbilt University Medical Center , National Institutes Of Health , Charlesc Gates Center , Vanderbilt University Medical Center , Amber Freed , Taysha Gene Therapies , Center Director , National Institutes , Medicine Health , Mental Health , ஒன்றுபட்டது மாநிலங்களில் , ஜெரால்ட் நுவோசு , அலெஜாண்ட்ரா ரொமெரோ மன உறுதியும் , விவியன் காமா ,

Antibody 'cocktails' effective against SARS-CoV-2 mutations

Antibody cocktails effective against SARS-CoV-2 variants
Written by Timothy Huzar on March 11, 2021 â Fact checked by Mary Cooke, Ph.D.
Numerous therapeutics have been developed to treat COVID-19.
However, many are based on initial variants of SARS-CoV-2 and may be less effective against recent ones.
In the present study, researchers have identified monoclonal antibody âcocktailsâ that are still effective against recent variants.
All data and statistics are based on publicly available data at the time of publication. Some information may be out of date.
for the most recent information on the COVID-19 pandemic.
In laboratory tests, a team of researchers has analyzed the efficacy of a range of COVID-19 antibody-based therapeutics against the latest variants of SARS-CoV-2. ....

James Crowe Jr , Ann Scott Carell , Robert Carnahan , Researchers At Vanderbilt University Medical Center , Vanderbilt Vaccine Center , University Of Texas , Drug Administration , Washington University School Of Medicine , Nature Medicine , Vanderbilt University Medical Center , Washington University School , Vir Biotechnology , James Crowe , Ann Scott Carell Professor , ஜேம்ஸ் காகம் ஜூனியர் , ஆண்டு ஸ்காட் கவனிப்பு , ராபர்ட் கார்னஹான் , ஆராய்ச்சியாளர்கள் இல் வாண்டர்பில்ட் பல்கலைக்கழகம் மருத்துவ மையம் , வாண்டர்பில்ட் தடுப்பூசி மையம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , இயற்கை மருந்து , வாண்டர்பில்ட் பல்கலைக்கழகம் மருத்துவ மையம் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , வீர் உயிரி தொழில்நுட்பவியல் , ஜேம்ஸ் காகம் ,

Researchers develop antibody 'cocktail' effective against all Covid-19 strains

Researchers develop antibody 'cocktail' effective against all Covid-19 strains
thehindubusinessline.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thehindubusinessline.com Daily Mail and Mail on Sunday newspapers.

South Africa , United Kingdom , James Crowe Jr , Researchers At Vanderbilt University Medical Center , Vanderbilt Vaccine Center , Vanderbilt University Medical Center , Nature Medicine , James Crowe , ஒன்றுபட்டது கிஂக்டம் , ஜேம்ஸ் காகம் ஜூனியர் , ஆராய்ச்சியாளர்கள் இல் வாண்டர்பில்ட் பல்கலைக்கழகம் மருத்துவ மையம் , வாண்டர்பில்ட் தடுப்பூசி மையம் , வாண்டர்பில்ட் பல்கலைக்கழகம் மருத்துவ மையம் , இயற்கை மருந்து , ஜேம்ஸ் காகம் ,

Over 20 dead, millions struggle without power as cold snap grips US

Over 20 dead, millions struggle without power as cold snap grips US
Agencies
February 17, 2021
Washington, Feb 17: Millions were left without power as a winter storm gripped the southern and central United States on Tuesday with record-low temperatures in ill-prepared areas, and a tornado claiming three lives.
More than 20 storm-related deaths have been registered so far, including in traffic accidents in Texas, Kentucky and Missouri, according to local media.
In hardest-hit Texas where freezing conditions prompted utility companies to implement rotating blackouts a woman and girl died from carbon monoxide poisoning after using a car to generate heat, according to NBC News. ....

United States , University Of Utah , United Kingdom , Feng Gao , South Africa , Vincent Munster , Mark Denison , Katrina Lythgoe , Stephen Goldstein , Sandra Weller , National Institute Of Allergy , Researchers At Vanderbilt University Medical Center , Oxford Big Data Institute , Jinan University , University Of Connecticut School Medicine , Nels Elde , Vanderbilt University Medical Center , National Institute , Infectious Diseases , Connecticut School , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் உட்டா , ஒன்றுபட்டது கிஂக்டம் , ஃபெங் கொ , வின்சென்ட் மன்ஸ்டர் , குறி மறுப்பு ,

06 February 2021 Coronavirus Charts and News: Concern Continues To Grow Over The Potential Impact Of The COVID-19 Mutation.

The U.S. new cases 7-day rolling average are 18.9 % LOWER than the 7-day rolling average one week ago. U.S. hospitalizations due to COVID-19 are now 12.8 %
LOWER than the rolling average one week ago. U.S. deaths due to coronavirus are now 0.1 %
HIGHER than the rolling average one week ago. Today s posts include:
U.S. Coronavirus New Cases are 133,558
U.S. Coronavirus hospitalizations are at 86,373
U.S. Coronavirus deaths are at an elevated 3,674 [are the new variants more deadly or are vaccinations impacting deaths - as hospitalizations have been contracting since mid-January?>
U.S. Coronavirus immunizations have been administered to 11.0 % of the population ....

New York , United States , United Kingdom , White House , District Of Columbia , South Africa , New Mexico , South African , Steven Hansen , Siobain Duffy , Janet Woodcock , Anthony Fauci , Eli Lilly , Andrew Ustianowski , Omar Alghabra , Nicky Longley , Rochelle Walensky , National Institute Of Allergy , National Geographic , University College London Hospitals , Washington Post , Centers For Disease , Drug Administration , Vaccine Administration Management System , New York Times , Researchers At Vanderbilt University Medical Center ,