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Know the scientist: Christiane Nusslein-Volhard


Updated:
April 29, 2021 10:22 IST
Her investigations in zebra fish have helped elucidate genes and other cellular substances involved in human development.
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Her investigations in zebra fish have helped elucidate genes and other cellular substances involved in human development.
Christiane Nusslein-Volhard is a German geneticist, who was the co-recipient of the 1995 Nobel Prize in Physiology or Medicine for her research on the mechanisms of early embryonic development.
Christiane Nusslein-Volhard was born in Heyrothsberge, Germany, in 1942. Christiane studied biology at Goethe University in Frankfurt and biochemistry at Eberhard-Karl University, Tubingen, before undertaking graduate studies at the Max Planck Institute.
Upon completing her PhD in genetics in 1973, Chritiane joined the University of Basel. There she undertook gene study on Drosophila, or fruit flies, an important model organism in genetics. In 1978, she joined the E ....

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Single Cell Transcriptomics Could Help Eradicate Leukemia More Effectively


Single Cell Transcriptomics Could Help Eradicate Leukemia More Effectively
March 1, 2021
Immature blood cells in leukemia [Source: toeytoey2530/Getty Images]
Research from an international collaboration shows that a single-cell omics approach can identify mutational status and characterize gene expression in hematopoietic stem cells from acute myeloid leukemia patients and successfully identify disease causing cells.
Treatments exist for acute myeloid leukemia (AML), but while these often succeed initially, patients often relapse. Indeed, less than 15% of patients over the age of 60 survive for 5 years after treatment for this reason.
“Only cancer stem cells, residing at the top of the hierarchy, are able to fuel long-term cancer growth and drive relapse, whereas the bulk of the cancer consists of rapidly dividing cells with limited capacity for self-renewal,” write the researchers in the journal article describing the study in ....

Comunidad Autonoma De Cataluna , Lars Velten , Lars Steinmetz , Heidelberg Institute For Stem Cell Technology , Centre For Genomic Regulation , European Molecular Biology Laboratory In Heidelberg , Group Leader , Stanford University , Genomic Regulation , European Molecular Biology Laboratory , Heidelberg Institute , Stem Cell Technology , Experimental Medicine , Nature Genetics , காமுனிடட தன்னாட்சி டி கடலுள் , லார்ஸ் சிடேன்மேடஜ் , ஹைடெல்பெர்க் நிறுவனம் க்கு தண்டு செல் தொழில்நுட்பம் , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆய்வகம் இல் ஹைடெல்பெர்க் , குழு தலைவர் , ஸ்டான்போர்ட் பல்கலைக்கழகம் , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆய்வகம் , ஹைடெல்பெர்க் நிறுவனம் , தண்டு செல் தொழில்நுட்பம் , சோதனை மருந்து , இயற்கை ஜெநெடிக்ஸ் ,

The AMR Action Fund announces its first non-industry investments, raising an additional US$140 million toward addressing antimicrobial resistance (AMR)


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BOSTON, Feb. 18, 2021 /PRNewswire/  Today, the AMR Action Fund announced its first initial close with non-pharmaceutical industry investments of more than US$140 million from the Boehringer Ingelheim Foundation, the European Investment Bank (supported by the European Commission), and the Wellcome Trust. This adds to the initial investment from more than 20 leading biopharmaceutical companies that established the Fund as announced in July 2020. With this significant financial commitment from global foundations and development banks, the AMR Action Fund becomes the world s largest public-private partnership supporting the development of new antibiotics. It demonstrates the type of commitment and collaboration across sectors that is urgently needed to address the global threat of antibiotic-resistant infections – also called antimicrobial resistance, or AMR. ....

United States , Baden Wuberg , Silas Holland , Henry Skinner , Jeremy Farrar , Hubertus Liebrecht , Eli Lilly , Christoph Boehringer , Werner Hoyer , Action Fund , Boehringer Ingelheim , Merck Kga , European Commission Under Horizon , European Molecular Biology Laboratory In Heidelberg , European Union , European Union Member States , Novo Nordisk Foundation , European Investment Bank , Institute Of Molecular Biology , University Of Mainz , World Health Organization , European Commission , Boehringer Ingelheim Foundation , Merck Kgaa , Perspectives Programme , Novo Nordisk ,