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Willpower is the key to enhancing learning and memory: researchers uncover the mechanism


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Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this reality had been identified in the brain of mice, their existence in our species had not been corroborated.
Now, an international group of researchers led by ICREA Research Professor Paul Verschure from the SPECS laboratory at the Institute for Bioengineering of Catalonia (IBEC) and Professor Nikolai Axmacher from the Department of Neuropsychology at Ruhr-Universität Bochum (Germany), in collaboration with Pompeu Fabra University and Dr. Rodrigo Rocamora from Hospital del Mar, have identified for the first time in humans, the mechanism responsible for this phenomenon. ....

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Common Antidepressants May not Raise the Risk of Stroke


Common Antidepressants May not Raise the Risk of Stroke
by Angela Mohan on 
March 1, 2021 at 12:20 PM
SSRIS may not raise the risk of intracerebral hemorrhage among patients with depression, as per the study that will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
An intracerebral hemorrhage is when a blood vessel bursts in the brain sending blood into the surrounding tissue. The most common causes are high blood pressure and head trauma, but some studies have also suggested that SSRIs may increase a person s risk of this type of bleeding stroke.
Selective serotonin reuptake inhibitors work by preventing reabsorption of the chemical serotonin, which regulates mood, into the cells, making more of it available in the brain, said study author Mithilesh Siddu, M.D., of the University of Miami in Florida and member of the American Academy of Neurology. ....

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NYU Oral Cancer Center awarded NIH grant to study interplay between oral cancer and nerves


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NYU Oral Cancer Center has been awarded a five-year, $3.1 million grant (R01 CA231396) by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). The principal investigators, Donna Albertson, PhD, and Brian Schmidt, DDS, MD, PhD, seek to improve oral cancer treatment and alleviate pain by better understanding how a subset of nerves that possess a receptor called TRPV1 on the cell membrane contribute to cancer progression and pain.
Oral cancer patients have a poor prognosis and endure debilitating pain. Albertson and Schmidt have been investigating oral cancer at the molecular level for nearly two decades to address these pressing clinical challenges. ....

Brian Schmidt , Donna Albertson , Nyu Oral Cancer Center , National Cancer Institute , College Of Dentistry , National Institutes Of Health , Oral Cancer Center , Cancer Center , National Institutes , Medicine Health , Dentistry Periodontal Disease , பிரையன் ஶ்மிட் , டோனா ஆல்பர்ட்சன் , நியூ வாய்வழி புற்றுநோய் மையம் , தேசிய புற்றுநோய் நிறுவனம் , கல்லூரி ஆஃப் பல் மருத்துவம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , வாய்வழி புற்றுநோய் மையம் , புற்றுநோய் மையம் , தேசிய நிறுவனங்கள் , மருந்து ஆரோக்கியம் , பல் மருத்துவம் பெரியடாஂடல் நோய் ,

A new theory for how memories are stored in the brain


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Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function. This discovery may be the beginning of a new understanding of brain function and in treating brain diseases such as Alzheimer s.
In a paper published by
Frontiers in Molecular Neuroscience, Dr Ben Goult from Kent s School of Biosciences describes how his new theory views the brain as an organic supercomputer running a complex binary code with neuronal cells working as a mechanical computer. He explains how a vast network of information-storing memory molecules operating as switches is built into each and every synapse of the brain, representing a complex binary code. This identifies a physical location for data storage in the brain and suggests memories are written in the shape of molecules in the synaptic scaffolds. ....

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Noisy brain activity contributes to aging-related navigation impairments


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IMAGE: In younger adults, hippocampal activity decreases and acitivty in other navigational areas increases. The pattern is not seen in older adults.
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Credit: Diersch et al., JNeurosci 2021
Too much activity in the hippocampus may cause navigation impairments seen in aging adults, according to new research published in
JNeurosci.
Spatial navigation is one of the cognitive abilities that declines sharply in old age. Older adults often have difficulty navigating new environments and will choose to stick with familiar ones. Plus, key regions in the brain s navigation circuit are some of the first affected by Alzheimer s disease. In a recent study, Diersch et al. examined the neural mechanism behind this decline in spatial learning. ....

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