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Cancer Find Up for Year's Biggest Biomedical Advance in a Different 'March Madness'

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Cancer Find Up for Year’s Biggest Biomedical Advance in a Different ‘March Madness’
For the third year in a row, a discovery from the University of Virginia School of Medicine has been selected as one of the year’s most significant biomedical discoveries. The finding – identifying the gene responsible for one of the deadliest cancers – is among 64 contenders fighting it out to win the public’s votes in an online bracket tournament.
Voting opens today for “STAT Madness,” which is like the scientific version of the NCAA basketball tournament. The annual competition is sponsored by the STAT health news site to identify the year’s “best biomedical innovation,” and you can vote by clicking here. The first round is open through Sunday. ....

K Craig Kent , School Of Medicine , Massachusetts Institute Of Technology , Cancer Center , University Of Virginia School Medicine , University Of Virginia Public , University Of Notre Dame , Rockefeller University , Department Of Pathology , Stanford University , Duke University , Virginia School , Notre Dame , Massachusetts Institute , Virginia Public , University Of Virginia , Type 1 Diabetes , Brain Cancer , Genetic Risk , கே கிரேக் கேண்ட் , பள்ளி ஆஃப் மருந்து , மாசசூசெட்ஸ் நிறுவனம் ஆஃப் தொழில்நுட்பம் , புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா பள்ளி மருந்து , பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா பொது , பல்கலைக்கழகம் ஆஃப் நோட்ரே டேம் ,

New type of ultrasound scan could improve outcome from brain tumor surgery

A type of ultrasound scan can detect cancer tissue left behind after a brain tumor is removed more sensitively than surgeons, and could improve the outcome from operations, a new study suggests. ....

City Of , United Kingdom , Kevin Harrington , Dagmar Krafft , Jeffrey Bamber , Neil Dorward , Emily Henderson , National Hospital For Neurology , Royal Free Charity , Head Of The Division Radiotherapy , Institute Of Cancer Research , University Hospital Southampton , Sciences Research Council , Cancer Research , National Hospital , Royal London Hospital , University Hospital , Physical Sciences Research Council , Professor Jeffrey Bamber , Physics Applied , Consultant Neurosurgeon , Brain Surgery , Brain Cancer , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , கெவின் ஹாரிங்டன் ,

New study challenges 'established' mechanism about selectivity of cellular ion channels

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IMAGE: Cell membranes contain channels that selectively permit ions to move into or out of the cell. In a recently published paper, researchers from the University of Fukui and Kanazawa University.
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Credit: University of Fukui
The cell membranes of all organisms contain ion channels that permit ions to pass into or out of the cell, and these channels play extremely important roles in fundamental physiological processes such as heartbeats and the rapid conduction of signals along neurons. An important property of these ion channels is their selective conductivity they selectively permit the passage of particular ions. For example, potassium channels more readily permit the passage of potassium ions than the passage of sodium ions, despite the fact that potassium ions are larger. ....

United States , Shigetoshi Oiki , Mika Hayashi , Bunkyo Fukui , Hiroe Yoneda , Scientific Research , Kanazawa University , University Of Fukui , Biomedical Imaging Research Center , Public Affairs , Nano Life Science Institute , Nano Life Science Institute Kanazawa University , Professor Shigetoshi Oiki , National Academy , Conductance Selectivity , Tortuous Trajectory , Long Residency Time , Specially Appointed , Fukui Faculty , Medical Sciences , Life Science Institute , Cell Biology , Molecular Biology , Chemistry Physics Materials Sciences , Biomechanics Biophysics , Research Development ,

Study: Treatable sleep disorder common in people with thinking and memory problems

Obstructive sleep apnea is when breathing is repeatedly interrupted during sleep. Research has shown people with this sleep disorder have an increased risk of developing cognitive impairment and Alzheimer s disease. Yet, it is treatable. A preliminary study released today, February 28, 2021, has found that obstructive sleep apnea is common in people with cognitive impairment. The study will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021. ....

United States , Davidr Colelli , Marki Boulos , American Academy Of Neurology Annual Meeting , University Of Toronto , American Academy Of Neurology , American Academy , Annual Meeting , Ontario Graduate Scholarship , Cognitive Neurology Research Unit , Sunnybrook Health Sciences Centre , Medicine Health , Sleep Disorders , Memory Cognitive Processes , ஒன்றுபட்டது மாநிலங்களில் , மார்க்கி பவுலோஸ் , அமெரிக்கன் கலைக்கழகம் ஆஃப் நரம்பியல் ஆண்டு சந்தித்தல் , பல்கலைக்கழகம் ஆஃப் டொராண்டோ , அமெரிக்கன் கலைக்கழகம் ஆஃப் நரம்பியல் , அமெரிக்கன் கலைக்கழகம் , ஆண்டு சந்தித்தல் , ஆஂடேரியொ பட்டதாரி உதவித்தொகை , அறிவாற்றல் நரம்பியல் ஆராய்ச்சி அலகு , சன்னிபிரூக் ஆரோக்கியம் அறிவியல் மையம் , மருந்து ஆரோக்கியம் , தூங்கு கோளாறுகள் ,

Predicts the onset of Alzheimer's Disease (AD) using deep learning-based Splice-AI

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IMAGE: High-throughput total RNA-seq profile for PLCγ1 and PLCβ subfamily gene expression in the cortex
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Credit: KBRI
Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI.
This research outcome was published in
PNAS, a world-renowned academic journal.
(Title) Prediction of Alzheimer s Disease-Specific phospholipase c gamma-1 SNV by Deep Learning-Based Approach for High-Throughput Screening
Alternative splicing variant regulates gene expression and influences diverse phenotypes. Especially, genetic variants arising due to RNA splicing are frequently found in individuals having neurodevelopmental disorders. ....

South Korea , Suh Pann Ghill , Jae Yeol Joo , National Research Foundation Of Korea , Korea Brain Research Institute , President Suh Pann Ghill , Deep Learning Based Approach , Fourth Industrial Revolution , National Research Foundation , Cell Biology , Health Care , Algorithms Models , Medicine Health , தெற்கு கொரியா , தேசிய ஆராய்ச்சி அடித்தளம் ஆஃப் கொரியா , கொரியா மூளை ஆராய்ச்சி நிறுவனம் , ஆழமான கற்றல் அடிப்படையிலானது அணுகுமுறை , நான்காவது தொழில்துறை புரட்சி , தேசிய ஆராய்ச்சி அடித்தளம் , செல் உயிரியல் , ஆரோக்கியம் பராமரிப்பு , மருந்து ஆரோக்கியம் ,