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Nanoparticles help untangle Alzheimer's disease amyloid beta plaques

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IMAGE: The amyloid beta protein that tangles to form the hallmark Alzheimer s brain plaques, cling to ultra-small bowls, called nanobowls, scientists find. They can use these nanobowls to remove the toxic.
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Credit: Illustration courtesy of Vrinda Sant.
ROCKVILLE, MD - Scientists are still a long way from being able to treat Alzheimer s Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study. The plaques are caused by the amyloid beta protein, which gets misshapen and tangled in the brain. To study these protein aggregates in tissue samples, researchers often have to use techniques that can further disrupt them, making it difficult to figure out what s going on. But new research by Vrinda Sant, a graduate student, and Madhura Som, a recent PhD graduate, in the lab of Ratnesh Lal at the University of California, San Diego, provides a new technique for studying amyloid be ....

United States , San Diego , Ratnesh Lal , Vrinda Sant , University Of California , Meeting Of The Biophysical Society , Madhura Som , Annual Meeting , Biomechanics Biophysics , Chemistry Physics Materials Sciences , Alzheimers Disease , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , றத்னேஷ் லால் , விரிந்த சந்த் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , சந்தித்தல் ஆஃப் தி உயிர் இயற்பியல் சமூகம் , மதுரா சோம் , ஆண்டு சந்தித்தல் , பயோமெக்கானிக்ஸ் உயிர் இயற்பியல் , உயிரி தொழில்நுட்பவியல் , வேதியியல் இயற்பியல் பொருட்கள் அறிவியல் , அல்சைமர் நோய் ,

Deep learning amyotrophic lateral sclerosis by taking pictures

Kyoto University
A team of scientists led by CiRA Professor Haruhisa Inoue reports the combination of deep learning and iPS cell technology for the diagnosis of amyotrophic lateral sclerosis (ALS).
For many devasting neurological diseases like Alzheimer’s disease and amyotrophic lateral sclerosis (ALS), patients are diagnosed only after becoming symptomatic. However, the evidence of memory and muscle loss is seen only after the disease has progressed to irreversible states. Researchers are therefore exploring ways to identify patients well before they become symptomatic, which could allow for wider clinical options.
“If we can catch the disease at the reversible stage, we may reverse and cancel the disease.” said CiRA Prof. Haruhisa Inoue, a specialist of ALS research using iPS cells. ....

Hideshi Kawakami , Haruhisa Inoue , Keiko Imamura , Yuichiro Yada , Mitsuya Morita , Kayoko Tsukita , Ryosuke Takahashi , Ayako Nagahashi , Masanori Nakagawa , Akihiro Kawata , Yuishin Izumi , Takayo Arisato , Department Of Clinical Neuroscience , Tokushima University Graduate School , Bioresource Research Center , School Of Medicine , Department Of Neurology , Institute For Advancement Of Clinical , Hiroshima University , Department Of Epidemiology , Kyoto University Hospital , Institute Of Biomedical Sciences , National Hospital Organization Minamikyusyu , Ps Cells Team , Department Of Internal Medicine , Ps Cell Research ,

The exercise pill: How exercise keeps your brain healthy and protects it against depression and anxiety

Many doctors believe that exercise is the closest thing to a miracle drug that modern medicine has in its arsenal. But have you ever wondered why that is so? Your brain actually benefits, too. ....

Richard Baker , Getty Images , Exercise And Health , ரிச்சர்ட் ரொட்டி சுடுபவர் , கெட்டி படங்கள் , உடற்பயிற்சி மற்றும் ஆரோக்கியம் ,

Repetitive compression of limbs appears to aid recovery from deadly brain bleeds

Credit: Kim Ratliff, Augusta University photographer
AUGUSTA, Ga. (Feb. 25, 2021) - Scientists want to know more about how an inexpensive, low-risk treatment may improve recovery from the most deadly type of stroke.
The treatment, remote ischemic conditioning, or RIC, involves successive bouts of compressing then relaxing an arm or leg with a blood pressure-like cuff, most typically for four cycles of five minutes of inflation followed by five minutes of deflation.
The most deadly stroke is an intracerebral hemorrhage, the most common form of hemorrhagic stroke, in which blood, which is toxic to brain tissue, spills out of blood vessels in the brain. ....

United States , Krishnan Dhandapani , Department Of Neurosurgery , Stroke Preclinical Assessment Network , National Institutes Of Health , Department Of Neurology Dr , College Of Georgia At Augusta University , Medical College , National Institutes , Medicine Health , Trauma Injury , ஒன்றுபட்டது மாநிலங்களில் , கிருஷ்ணன் தண்டபாணி , துறை ஆஃப் நரம்பியல் அறுவை சிகிச்சை , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , துறை ஆஃப் நரம்பியல் டாக்டர் , கல்லூரி ஆஃப் ஜார்ஜியா இல் அகஸ்டா பல்கலைக்கழகம் , மருத்துவ கல்லூரி , தேசிய நிறுவனங்கள் , மருந்து ஆரோக்கியம் , அதிர்ச்சி காயம் ,

'Exercise hormone' could prevent weight gain and maintain healthy muscles

A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings. ....

United States , Su Jeong Kim , Hirofumi Zempo , Seiji Maeda , Hemal Mehta , Pauloj Oliveira , Pinchas Cohen , Amy Huang , Raquel Coelho , Changhan David Lee , Hiroshi Kumagai , Noriyuki Fuku , Faculty Of Health , Cohbar Inc , University Of Tsukuba , School Of Health , Sport Sciences , Leonard Davis School , Juntendo University , Leonard Davis School Of Gerontology , University Of Coimbra , Southern California Leonard Davis School , American Journal , Davis School , Graduate School , Sports Science ,