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Discovery of a new genetic cause of hearing loss illuminates how inner ear works

PHILADELPHIA A gene called
GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.
Developmental Cell, discovered that the protein encoded by
GAS2 is crucial for maintaining the structural stiffness of support cells in the inner ear that normally help amplify incoming sound waves. They showed that inner ear support cells lacking functional
GAS2 lose their amplifier abilities, causing severe hearing impairment in mice. The researchers also identified people who have
GAS2 mutations and severe hearing loss. ....

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Penn study reveals how opioid supply shortages shape emergency department prescribing behaviors

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PHILADELPHIA When evaluating the opioid crisis, research reveals that external factors - such as the volume of pre-filled syringes, or a default number of opioid tablets that could easily be ordered at discharge for the patient - can shift prescribing and compel emergency department (ED) physicians to administer or prescribe greater quantities of opioids. A new study published in the
Journal of Medical Toxicology reveals that opioid prescribing behavior can also be decreased by external factors, such as a supply shortage.
Led by the Perelman School of Medicine at the University of Pennsylvania, researchers evaluated pharmacy data from the electronic medical records (EMR) collected before, during, and after a period of parenteral opioid shortage across two large urban academic emergency departments - the Hospital of the University of Pennsylvania and University Hospital in Newark, New Jersey. In this case, the shortage was of parenteral morphine and hydromor ....

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$3.5 Million Grant Supports Effort Led by Penn Medicine to Diversify Alzheimer's Disease Research

$3.5 Million Grant Supports Effort Led by Penn Medicine to Diversify Alzheimerâs Disease Research
Penn and community organizations partnering to address Alzheimerâs disease health disparities
Newswise PHILADELPHIA Black adults are more likely than other groups to develop Alzheimer s disease or related disorders but are poorly represented in Alzheimer’s disease research, including recent clinical trials. This health disparity illustrates how Black individuals can benefit from advances in the field if they had access.
This week, the Pennsylvania Department of Health’s Commonwealth Universal Research Enhancement (CURE) program announced it will award a $3.5 million grant to Penn Medicine researchers and community partners to address the underrepresentation of Black adults in Alzheimer’s Disease research. The grant supports the Aging Brain Cohort Dedicated to Diversity (ABCD ....

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Manatt Continues Hybridized Legal and Consulting Growth With Latest Health Care Additions in Washing

Manatt Continues Hybridized Legal and Consulting Growth With Latest Health Care Additions in Washing
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Manatt Continues Hybridized Legal and Consulting Growth With Latest Health Care Additions in Washington, D.C.
May 05, 2021
Linda Elam’s extensive health care management and managed care experience paired with Blair Cantfil’s complex regulatory and policy capabilities strengthen firm’s integrated offerings
Manatt, Phelps & Phillips, LLP, a multidisciplinary, integrated professional services firm, announced today that Managing Director Linda Elam and Partner Blair M. Cantfil are joining its Manatt Health Group in Washington, D.C. Elam and Cantfil’s arrival underscores Manatt’s continued commitment to expanding its national legal and consulting model with top talent across the firm. ....

Georgetown University Law Center , District Of Columbia , United States , Ralphw Muller , Briand Bewley , Jen Millard , Kalon Gutierrez , Blair Cantfil , Farnazm Alemi , Rustinm Brown , Phelps Phillips , Thomasw Michael , Paula Carr Rollitt , Donnal Wilson , Linda Elam , Blairm Cantfil , Darrellg Kirch , Johns Hopkins University , International Affairs At Princeton University , University Of Pennsylvania Health System , Manatt Health , Howard University , University Of California At Berkeley , Manatt Health Group , Princeton School Of Public , Association Of American Medical Colleges Dr ,

Think You Have Penicillin Allergy? You May Not

Think You Have Penicillin Allergy? You May Not
May 3, 2021 Most people whose medical records say they are allergic to penicillin may not actually be, an allergist said Thursday during the American College of Physicians Internal Medicine Meeting 2021.
The mis-diagnosis of an penicillin allergy may be dangerous and hurts efforts to fight antibiotic resistance, said Olajumoke Fadugba, MD, program director for the Allergy and Immunology Fellowship at the University of Pennsylvania Health System in Philadelphia.
About 10% of the population reports a history of penicillin allergy , but up to 90% of them are actually able to tolerate penicillin, Fadugba said. The mislabeling comes either because previous reactions were mischaracterized or people have outgrown the allergy. ....

University Of Pennsylvania , United States , Rush University Medical Center , Olajumoke Fadugba , Josune Iglesias , University Of Pennsylvania Health System , American College Of Physicians Internal Medicine Meeting , American College , Physicians Internal Medicine Meeting , Immunology Fellowship , Pennsylvania Health System , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , ஒன்றுபட்டது மாநிலங்களில் , அவசரம் பல்கலைக்கழகம் மருத்துவ மையம் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா ஆரோக்கியம் அமைப்பு , அமெரிக்கன் கல்லூரி ஆஃப் மருத்துவர்கள் உள் மருந்து சந்தித்தல் , அமெரிக்கன் கல்லூரி , மருத்துவர்கள் உள் மருந்து சந்தித்தல் , நோயெதிர்ப்பு கூட்டுறவு , பென்சில்வேனியா ஆரோக்கியம் அமைப்பு ,