15 Biggest Companies That Use Shopify Shopify is a subscription-based e-commerce platform that enables people to create an online store and sell their goods. Users can create a basic online store in seconds or create a unique store with features that draw more traffic and eventually translate to sales. Shopify Inc. (NYSE: SHOP) is one of the biggest and most profitable e-commerce companies in the world with a market cap of $141.3 billion. Shopify has expanded in recent years as a result of the boom in e-commerce that attracted many small businesses, and saw an enormous surge during the pandemic as more businesses were pressured to broaden their online presence. Shopify holds 8.6% of the U.S. retail e-commerce market in 2020, trailing online retail giant Amazon.com Inc. (NASDAQ: AMZN). Shopify’s revenue in 2020 skyrocketed to $2.9 billion, an increase of 86% over 2019.