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A tripartite-chromosome E. coli strain allows the chromosome isolation and implantation


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IMAGE: The E. coli chromosome was split into three 1-Mb chromosomes, and the chromosome was used for genome implantation.
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Credit: Rikkyo University
Escherichia coli (
E. coli) genome, consisting of 4.6 million base pairs of a single circular DNA, is too large to manipulate following the extraction and transfer to other bacteria.
In the present study, a group of Rikkyo University researchers led by Assistant Professor Takahito Mukai and Professor Masayuki Su etsugu has succeeded in splitting the E.coli genome into tripartite-genome of 1 million base pairs per genome (split-genome) using the smallest
E. coli genome strain established so far. In addition, they successfully extracted the split-genome from bacteria and installed it in other ....

Takahito Mukai , Masayuki Suetsugu , Nucleic Acids Research On , Rikkyo University , Strategic Basic Research Program , Core Research For Evolutional Science , Assistant Professor Takahito Mukai , Professor Masayuki Su Etsugu , Nucleic Acids Research , Basic Research Program , Core Research , Evolutional Science , Molecular Biology , றிக்கியோ பல்கலைக்கழகம் , மூலோபாய அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , கோர் ஆராய்ச்சி ,

New, biological, and safer soaps


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IMAGE: INRS Professor Charles Gauthier, specialist in chemistry of carbohydrates and natural products, who led the research.
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Credit: Christian Fleury
An international research team led by Professor Charles Gauthier from the Institut national de la recherche scientifique (INRS) has discovered a new molecule with potential to revolutionize the biosurfactant market. The team s findings have been published in
Surfactants are synthesized from petroleum and are the main active ingredient in most soaps, detergents, and shampoos. Biosurfactants, produced by bacteria, are safer and can replace synthetic surfactants.
Rhamnolipid molecules are some of the safest surfactants known and are particularly attractive, thanks to their biodegradability, minimal toxicity, and amenability to be produced from industrial waste. But there s a problem. They are made using Pseudomonas aeruginosa, a pathogenic bacterium harmful to humans. ....

Thomas Feroldi , Charles Gauthier , Marie Christine Groleau , Marianne Piochon , Armand Frappier Sant , Mayri Alejandra , Maude Cloutier , Serge Lavoie , Terre Environnement , Jean Legault , Sandra Villaume , Royal Society Of Chemistry , Engineering Research Council Of Canada , Natural Sciences , Liverpool John Moores University , Professor Charles Gauthier , Chemical Science , Royal Society , Vanier Canada Graduate Scholarship , Engineering Research Council , Quebec City , Eau Terre Environnement , Urbanisation Culture Soci , Biomedical Environmental Chemical Engineering , Molecular Biology , Business Economics ,

Study led by NTU Singapore finds that microbes work as a network in causing lung infection


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IMAGE: NTU LKCMedicine Asst Prof Sanjay Chotirmall and his team believe that their proposed concept of understanding infections applies to all forms of infection, and could potentially offer fresh ways of.
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Credit: NTU Singapore
Traditionally, an infection is thought to happen when microbes - bacteria, fungi, or viruses - enter and multiply in the body, and its severity is associated with how prevalent the microbes are in the body.
Now, an international research team led by Nanyang Technological University, Singapore (NTU Singapore) has proposed a new way of understanding infections. Their study of close to 400 respiratory samples from patients with bronchiectasis, a chronic lung condition, has shown that microbes in the body exist as a network, and that an infection s severity could be a result of interactions between these microbes. ....

Tan Tock Seng Hospital , Singapore General , New South Wales , United Kingdom , City Of , Sanjay Haresh Chotirmall , Foo Jie Ying , John Abisheganaden , Granda Ospedale Maggiore Policlinico , S Rajaratnam School Of International , Nanyang Technological University , Lee Kong Chian School Of Medicine , National Institute Of Education , Singapore Centre For Environmental Life Sciences Engineering , University Of Sydney , University Of Malaya , Imperial College London , Corporate Communications Office , Nanyang Environment Water Research Institute , Energy Research Institute , University Of Milan , University Of Exeter , University Of Dundee , Nature Medicine , Professor Sanjay Haresh Chotirmall , Kong Chian School ,

New cyanobacteria species spotlights early life


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IMAGE: Anthocerotibacter panamensis, a newly discovered species of cyanobacteria, can help researchers study the dawn of oxygenic photosynthesis.
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Credit: Fay-Wei Li
ITHACA, NY, May 13, 2021 Cyanobacteria are one of the unsung heroes of life on Earth. They first evolved to perform photosynthesis about 2.4 billion years ago, pumping tons of oxygen into the atmosphere - a period known as the Great Oxygenation Event - which enabled the evolution of multicellular life forms.
Led by BTI faculty member Fay-Wei Li, researchers have discovered a new species of cyanobacteria, Anthocerotibacter panamensis, which could help illuminate how photosynthesis evolved to create the world as we know it. The work was published in ....

T Ai Pei , National Taiwan University , Jessicam Nelson , Juan Carlos Villarreal , Nasim Rahmatpour , Fay Wei Li , Pa Yu Chen , Duncana Hauser , Laval University , Cornell University , Us National Science Foundation , Great Oxygenation Event , Current Biology , Science Foundation , Ecology Environment , Plant Sciences , Earth Science , டி ஐ பேய் , தேசிய டைவாந் பல்கலைக்கழகம் , லாவள் பல்கலைக்கழகம் , கார்னெல் பல்கலைக்கழகம் , எங்களுக்கு தேசிய அறிவியல் அடித்தளம் , தற்போதைய உயிரியல் , அறிவியல் அடித்தளம் ,