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A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.
E-Mail Researchers have discovered that the common bacteria E. coli can be deployed as a sustainable way to convert post-consumer plastic into vanillin, a new study reveals. Vanillin is the primary component of extracted vanilla beans and is responsible for the characteristic taste and smell of vanilla. The transformation could boost the circular economy, which aims to eliminate waste, keep products and materials in use and have positive impacts for synthetic biology, experts say. The world's plastic crisis has seen an urgent need to develop new methods to recycle polyethylene terephthalat...
E-Mail Chestnut Hill, Mass. (6/10/2021) - A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy. Published recently in the journal Frontiers in Nutrition, the report is the first evaluation of the use of ketogenic metabolic therapy (KMT) without chemo or radiation interventions, on a...
E-Mail A new study identifies a novel biomarker indicating resilience to chronic stress. This biomarker is largely absent in people suffering from major depressive disorder, and this absence is further associated with pessimism in daily life, the study finds. Nature Communications published the research by scientists at Emory University. The researchers used brain imaging to identify differences in the neurotransmitter glutamate within the medial prefrontal cortex before and after study participants underwent stressful tasks. They then followed the participants for four weeks, using a sur...
IMAGE: (Left) The number of hypermethylated DNA regions in both neuronal and non-neuronal cells is reduced in the bipolar patient group (BD) compared to the healthy group (CT). Credit: Professor Kazuya Iwamoto A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD). The regions with altered DNA methylation status were significantly enriched in genomic regions which were reported to be genetically related to BD. These findings are expected to ad...