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Mayo Clinic Q & A: What to expect during a blood draw

DEAR MAYO CLINIC: I've never had my blood drawn before, but I have to go in for testing soon. Honestly, I'm pretty nervous about it. What can I expect?

Phoenix , Arizona , United-states , Fiona-craig , Mayo-clinic-news-network , Tribune-content-agency , Laboratory-medicine , Mayo-clinic , Clinic-news , Hematology , Lood-tests , Hlebotomy

Low-molecular weight heparin bridging therapy safe in elderly undergoing surgery following percutaneous coronary intervention

Impact of perioperative low-molecular-weight heparin therapy on clinical events of elderly patients with prior coronary stents implanted > 12 months undergoing non-cardiac surgery: a randomized, placebo-controlled trial 1. A randomized control trial found low-molecular weight heparin (LMWH) bridging therapy did not increase the frequency of perioperative acute myocardial infarction (MI), cardiac death, stroke, or major

China , Chinese , Rating-level , Cardiology , Myocardial-infarction , Pci , Thrombosis , Chronic-disease , Hematology , Surgery ,

#VisualAbstract: Imetelstat improves blood transfusion independence in lower-risk myelodysplastic syndromes

1. Significantly more patients in the imetelstat group achieved RBC transfusion independence at 8 weeks after treatment compared to placebo. 2. Grade 3-4 treatment-related adverse events were greater in the imetelstat group. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with red blood cell transfusion-dependent lower-risk myelodysplastic syndromes (LR-MDS) face unmet medical needs when unresponsive to erythropoiesis-stimulating

Blood-transfusion , Erythropoeisis-stimulating-agents-esas- , Esa , Febrile-neutropenia , Hematology , Imetelstat , Myelodysplastic-syndrome , Myelodysplastic-syndromes , Neutropenia , Studygraphics ,

Novel prophylactic anticoagulation scoring tool helps stratify patients following lower limb trauma

1. The 3-month symptomatic venous thromboembolism rate was 0.7% in patients with TRiP(cast) score < 7 and not receiving anticoagulation. 2. There was no significant difference between the control and intervention phases regarding secondary outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Venous thromboembolism (VTE) is a well-recognized potential complication resulting from orthopedic trauma and

Belgium , France , Rating-level , Thrombosis-risk-prediction , Cast-immobilization , Low-molecular-weight-heparin , Between-jun , Ral-anticoagulation , Anticoagulation , Lower-limb-injury , Lower-limb-trauma

#VisualAbstract: Iptacopan improves hematologic and clinical outcomes in paroxysmal nocturnal hemoglobinuria

1. In two clinical trials, iptacopan in patients with paroxysmal nocturnal hemoglobinuria (PNH) improved hemoglobin levels compared to anti-C5-treated patients and those without complement inhibitors. 2. Patients who received iptacopan generally exhibited improved secondary outcomes, including less fatigue, reduced reticulocyte and bilirubin levels, and decreased breakthrough hemolysis. Evidence Rating Level: 1 (Excellent) Study Rundown: PNH is a

Hematology , Iptacopan , Paroxysmal-nocturnal-hemoglobinuria , Pnh , Studygraphics ,

Nebraska Community Blood Bank declares emergency due to low supply, urges donations

NCBB said that they are still recovering from a nearly 50% decrease in youth and first-time blood donors since 2019, and are working to rebuild donations.

Nebraska , United-states , Cheryl-warholoski , Nebraska-community-blood-bank , Drug-administration , Executive-director , Nebraska-community-blood , Health-medical-pharma , Europe , Ncbb , Hematology , Transfusion-medicine

Central City residents charged after infant found with bruising inside uninhabitable home

Two Central City residents have been charged after an infant was found with significant bruising on his body inside an uninhabitable home.

Brittney-bryant , Jeffrey-bryant , Merrick-county-court , Two-central-city , Law-crime , Social-care-in-england , Hematology , Refrigerator , Bruise , Injuries , Killing-of-peter-connelly ,

Iptacopan improves hematologic and clinical outcomes in paroxysmal nocturnal hemoglobinuria

1. In two clinical trials, iptacopan in patients with paroxysmal nocturnal hemoglobinuria (PNH) improved hemoglobin levels compared to anti-C5-treated patients and those without complement inhibitors. 2. Patients who received iptacopan generally exhibited improved secondary outcomes, including less fatigue, reduced reticulocyte and bilirubin levels, and decreased breakthrough hemolysis. Evidence Rating Level: 1 (Excellent) Study Rundown: PNH

Minute-medicine-inc , Rating-level , Complement-inhibitors , Hematology , Internal-medicine , Iptacopan , Paroxysmal-nocturnal-hemoglobinuria ,

Concomitant selective serotonin reuptake inhibitors and oral anticoagulants may increase risk of bleeding

1. This case-control study found that in patients with atrial fibrillation concomitant Serotonin Reuptake Inhibitor (SSRI) and Oral Anticoagulants (OAC) was associated with an increased risk of major bleeding compared with OAC use alone. 2. This increased risk was highest in the first 30 days of continuous, concomitant use. Evidence Rating Level: 2 (Good) Antidepressants,

United-kingdom-clinical-practice-research-datalink , Serotonin-reuptake-inhibitor , Oral-anticoagulants , Rating-level , Anticoagulation , Atrial-fibrillation , Cardiology , Depression , Psychiatry , Ssri , Hematology

Summerville woman using grief as a catalyst to help others

The blood donations of a Summerville woman has measured in the gallons since the death of her son.“Love is the strongest force, so I try to live that,” Becky Sh

Georgia , United-states , Becky-sharpe , Compassionate-friends , Ian , Human-interest , Summerville , Health-medical-pharma , Cultural-depictions-of-arthur-wellesley , St-duke-of-wellington , Blood-donation