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Adding time-restricted eating to calorie restriction does not provide added benefits in adults with obesity and nonalcoholic fatty liver disease.

Amgen's battle with Sanofi and Regeneron at the Supreme Court over its cholesterol drug Repatha on Monday has some drugmakers hoping a ruling will reshape US patent law and competition among companies that make antibody medicines.

Amgen sought to convince the US Supreme Court on Monday to revive patents on its cholesterol-lowering drug Repatha, while rival Sanofi urged the justices not to stifle competition for therapies to address a common health risk.

Some patients with side-effect concerns aiming to lessen their statin burden may prefer the treat-to-target approach, if they respond well to lesser-intensity statins, say researchers.

Risk factors for statin intolerance include female sex, obesity, hypothyroidism, diabetes, antiarrhythmics, alcohol use, exercise, chronic liver disease, and chronic kidney failure, studies suggest.