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Two Biosimilars Approved in Europe for Autoimmune Disorders

The drugs are intended to treat several types of arthritis, psoriasis, COVID-19, and Crohn's disease.

Ukraine , China , Bulgaria , Poland , Georgia , United-states , European-union , Medicinal-products , Human-use , European-medicines-agency , Rheumatoid-arthritis-ra

The Patient Knows Best: PROs in RA Practice and Research

Advanced systems for measuring patient-reported outcomes can help improve care of patients with rheumatoid arthritis and inform clinical research.

United-states , China , Boston , Massachusetts , Spain , Hospital-for-special-surgery , New-york , Baltimore , Maryland , National-institutes-of-health , Chinese , Cliftono-bingham

Investigators Train AI Systems to Predict RA Outcomes

Plugging massive amounts of data from EHRs into AI systems may turn masses of silicon chips into crystal balls for foretelling treatment efficacy.

New-york , United-states , Hospital-for-special-surgery , Jinoos-yazdany , Informatics-lab , Rheumatoid-arthritis-research-summit-ra , Stanford-university , Arthritis-foundation , University-of-california-san-francisco , Health-assessment-questionnaire , Zuckerberg-san-francisco-general-hospital , California-san-francisco

Sub-Q Tocilizumab Gives Durable Long-Term Responses in JIA

Patients with juvenile idiopathic arthritis achieved long-term disease control with subcutaneous tocilizumab treatment, without any new safety concerns, in an LTE study of two trials.

Cincinnati , Ohio , United-states , Herminei-brunner , International-league , Cincinnati-children , Hospital-medical-center , Juvenile-rheumatoid-arthritis , Uvenile-ra , Uvenile-idiopathic-arthritis , Arthritis

High Infection Risk in RA-Associated ILD

A prospective study found that 96% of patients with RA-ILD had at least one serious infection, which proved fatal in 65% of cases.

Spain , Plataforma-bionand , Natalia-mena , Natalia-mena-v , Instituto-de-investigaci , Rheumatoid-arthritis-ra , Heumatoid-arthritis-ra- , Skin-and-soft-tissue-infection , Urinary-tract-infection-uti , Streptococcal , Interstitial-lung-disease

Bone Infections Increase After S aureus Bacteremia in RA

The use of orthopedic implants or tumor necrosis factor inhibitors doubled the risk for bone infections in patients with RA who had contracted S aureus bacteremia.

Denmark , Glostrup , Sjæand , Copenhagen , Køavn- , Danish , Sabines-dieperink , Copenhagen-university-hospital , Centre-of-head , Copenhagen-university-hospital-rigshospitalet , Rheumatoid-arthritis-ra

Tuberculosis Screening Gaps Persist in New DMARD Users

Substantial patient safety gaps regarding latent tuberculosis screening persist among new users of biologic or targeted synthetic DMARDs, suggested a nationwide cohort study.

California , United-states , San-francisco , Erict-roberts , University-of-california , Arthritis-care-research , Hispanic-white , Arthritis-care , Biologic-therapy , Iologics , Tuberculosis-tb

Multiple Social Disadvantages Worsen Kids' Rheumatic Disease

Two recent studies revealed the compounding effects of negative social determinants of health on worse disease presentation and activity over time.

Ohio , United-states , Massachusetts , Boston , Alabama , Illinois , Ohio-state-university , Stacyp-ardoin , William-daniel-soulsby , Joycec-chang , Rheumatology-research-alliance , Ohio-state-university-in-columbus

Can Gut Microbiota Predict Multifactorial Disease Risk?

Research suggested that bacteria alone do not play an important role in determining disease risk.

Brazil , Rocha-fernandes , Dan-linetzky-waitzberg , Danielle-fonseca , Faculty-of-medicine-the-university , Medscape-portuguese , Microbiome , Icrobiota , Arthritis , Oint-inflammation , Bacteria , Acterial-infection

Can Microbiome Shifts Predict DMARD Response in RA?

An observational study in the United Kingdom found that patients with RA who started taking antirheumatic drugs had changes in their microbiome after 6 and 12 weeks.

New-york-university , New-york , United-states , London , City-of , United-kingdom , Nathan-danckert , Maxim-freidin , Greggj-silverman , York-university-school-of-medicine , Queen-mary-university-of-london , King-college-london