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The temporal evolution of SARS-CoV-2 vaccine efficacy and effectiveness (VE) against infection, symptomatic, and severe COVID-19 is incompletely defined. The temporal evolution of VE could be dependent on age, vaccine types, variants of the virus, and geographic region. We aimed to conduct a systematic review and meta-analysis of the duration of VE against SARS-CoV-2 infection, symptomatic COVID-19 and severe COVID-19. MEDLINE, Scopus, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, the World Health Organization Global Literature on Coronavirus...

The activity of marine microorganisms depends on community composition, yet, in some oceans, little is known about the environmental and ecological processes that structure their distribution. The objective of this study was to test the effect of geographic distance and environmental parameters on prokaryotic community structure in the Southern Ocean (SO). We described the total (16S rRNA gene) and the active fraction (16S rRNA-based) of surface microbial communities over a ~6.500 km longitudinal transect in the SO. We found that the community composition of the total fraction was different fr...

This US Preventive Services Task Force modeling study provides updated estimates of the net balance in benefits and harms of routine use of low-dose aspirin for

Aortic aneurysm (AA) is a global public health concern. However, little is known about the disease burden of AA in China. Following the general analytic strategy used in the Global Burden of Disease Study (GBD) 2019, we analyzed the mortality and years of life lost (YLLs) due to AA, stratified by sex, age, and province-level region in China from 1990 to 2019. The temporal trend of AA burden in China was analyzed and the main attributable risk factors for AA in China were also explored. In China, the total AA deaths were 17,038 (95% UI: 14,392-19,980) in 2019, an increase of 136.1% compared wit...

Klára Dán von Neumann arrives in Princeton, N.J., just as war breaks out in Europe