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Association of physical activity intensity and bout length with mortality: An observational study of 79,503 UK Biobank participants

Association of physical activity intensity and bout length with mortality: An observational study of 79,503 UK Biobank participants
plos.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from plos.org Daily Mail and Mail on Sunday newspapers.

United Kingdom , City Of , United Kingdom Medical Research Council , Information Centre , Medtronic Ltd , World Health Organization , University Of Bristol , University Of Bristol Vice , United Kingdom Biobank , Bristol Vice Chancellor , Roche Diagnostics , Observational Studies , World Health , Kingdom Biobank , United Kingdom National Health Service , National Research Ethics Service , Physical Activities , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் மருத்துவ ஆராய்ச்சி சபை , தகவல் மையம் , மெதிடிறோனிக் லிமிடெட் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் துணை , பிரிஸ்டல் துணை அதிபர் ,

SARS-CoV-2 testing and sequencing for international arrivals reveals significant cross border transmission of high risk variants into the United Kingdom

SARS-CoV-2 testing and sequencing for international arrivals reveals significant cross border transmission of high risk variants into the United Kingdom
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

Eteläuomen Läi , United Kingdom , Kaiya Chowdhary , Marco Loddo , Ruben Brandao , Alex Llewelyn , Keeda Marie Hardisty , Gareth Williams , Health Research Authority , National Research Ethics Service , United Kingdom Government , Supplementary Table , Virus Inactivation Medium , Trafalgar Scientific , Acid Isolation Kit , Thermo Fisher Scientific , Viral Transport Medium , Kingfisher Flex , ஒன்றுபட்டது கிஂக்டம் , கரேத் வில்லியம்ஸ் , ஆரோக்கியம் ஆராய்ச்சி அதிகாரம் , தேசிய ஆராய்ச்சி நெறிமுறைகள் சேவை , ஒன்றுபட்டது கிஂக்டம் அரசு , துணை மேசை , தெர்மோ மீனவர் அறிவியல் , வைரஸ் போக்குவரத்து நடுத்தர ,

Trends in HIV incidence between 2013–2019 and association of baseline factors with subsequent incident HIV among gay, bisexual, and other men who have sex with men attending sexual health clinics in England: A prospective cohort study

Trends in HIV incidence between 2013–2019 and association of baseline factors with subsequent incident HIV among gay, bisexual, and other men who have sex with men attending sexual health clinics in England: A prospective cohort study
plos.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from plos.org Daily Mail and Mail on Sunday newspapers.

United Kingdom , New York , United States , Brighton And Hove , East Sussex , City Of , South Wales , San Francisco , Alisonj Rodger , Richard Gilson , Janey Sewell , Omarion Campbell , Simon Collins , Andrew Speakman , Celia Richardson , Nadia Hanum , David Asboe , Elaney Youssef , Fionac Lampe , Nneka Nwokolo , Emmi Suonpera , Rosanna Laverick , Marzena Orzol , Susan Marie Graham , Amanda Clarke , Andrewn Phillips ,

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

Abstract
While it is now widely accepted that host inflammatory responses contribute to lung injury, the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from other viral lung diseases remain poorly characterized. We analyzed plasma samples from 471 hospitalized patients recruited through the prospective multicenter ISARIC4C study and 39 outpatients with mild disease, enabling extensive characterization of responses across a full spectrum of COVID-19 severity. Progressive elevation of levels of numerous inflammatory cytokines and chemokines (including IL-6, CXCL10, and GM-CSF) were associated with severity and accompanied by elevated markers of endothelial injury and thrombosis. Principal component and network analyses demonstrated central roles for IL-6 and GM-CSF in COVID-19 pathogenesis. Comparing these profiles to archived samples from patients with fatal influenza, IL-6 was equally elevated in both conditions whereas GM-CSF was prominent on ....

United Kingdom , United States , City Of , La Jolla , Oxford Immunotech , Jeremyj Farrar , Quanterix Billerica , Nahoko Shindo , Milliporesigma Burlington , Ethics Review Committee , Imperial Biomedical Research Centre , Scotlanda Research Ethics Committee Ref , Oxfordc Research Ethics Committee , Material Access Committee , Zoonotic Infections At University Of Liverpool , Health Protection Research Unit , World Health Organization , Tissue Bank Ethics Committee Approval , Health Protection Research Senior Investigator , Liverpool Experimental Cancer Medicine Centre , Infections At Imperial College London , United Kingdom Coronavirus Immunology Consortium , National Institute For Health Research United Kingdom , Fulham Research Ethics Committee , Department For International Development , Melinda Gates Foundation ,

Non-pharmacological alternatives to pro re nata psychotropic medication

Innovation
22 February, 2021
A survey explored non-pharmacological interventions as alternatives to
pro re nata (as-required) psychotropic medication in mental health settings. This article explores its results, which have been developed into a clinical aid suggesting possible interventions. This article comes with a handout for a journal club discussion
Abstract
Pro re nata (as-required) psychotropic medicines are used frequently in mental health settings; however, concerns have been raised over the safety and lack of evidence of effectiveness of this practice. A mental health trust conducted a survey exploring the non-pharmacological interventions used by nurses to support agitated service users. It used their responses to create a clinical aid that maps out suggested interventions under the themes of physical health, relaxation, distraction, environment and psychological health. ....

Douglas Hall , Dumfries And Galloway , United Kingdom , Greater Manchester , United Kingdom General , United States , City Of , Churchill Livingstone , Rowen Price , United Kingdom Workplace Stress , Research Methods For Clinical Therapists , Qualitative Research In Psychology , Royal College Of Psychiatrists , Management In Mental Health , British National Formulary , Research Ethics Committee , International Journal Of Mental Health Nursing , International Journal For Quality , University Of Manchester , Mental Health Nursing , Community Settings , National Institute For Health , International Journal Of Neuroscience , Psychiatric Services , Royal College Of Pyschiatrists , International Journal Of Nursing ,