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Milken Institute, Baszucki Brain Research Fund launch fund for bipolar disorder research

Credit: Milken Institute
The Milken Institute s Center for Strategic Philanthropy and the Baszucki Brain Research Fund today announced the launch of a dedicated grant program aimed at advancing therapeutic discovery for bipolar disorder (BD). The goal is to fund research with the potential to improve treatment options for affected individuals.
The Fund intends to award up to ten research grants in this cycle, providing up to $200,000 over the course of one year to support pilot research in therapeutic discovery and translational efforts. Together, these grants will amount to up to $2 million in new research dollars in the space.
The Baszucki Brain Research Fund has chosen to invest in a chronically underfunded and understudied mental health condition, providing capital that would not otherwise be available to researchers, said ....

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Brain damage caused by plasticisers

Bisphenols contained in many everyday objects can impair important brain functions in humans. Biologists from the University of Bayreuth warn of this danger in an article in Communications Biology. Their study shows that even small amounts of the plasticisers bisphenol A and bisphenol S disrupt the transmission of signals between nerve cells in the brains of fish. The researchers consider it very likely that similar interference can also occur in the brains of adult humans. ....

Stefan Schuster , Peter Machnik , Elisabeth Schirmer , Communications Biology , University Of Bayreuth , Animal Physiology , Cell Biology , Molecular Biology , Industrial Engineering Chemistry , ஸ்டீபன் ஸ்கஸ்டர் , தகவல்தொடர்புகள் உயிரியல் , விலங்கு உடலியல் , செல் உயிரியல் , மூலக்கூறு உயிரியல் , தொழில்துறை பொறியியல் வேதியியல் ,

Spit samples uncover genetic risk factors for paediatric obsessive-compulsive disorder

University of Calgary and The Hospital for Sick Children (SickKids) researchers have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth. Saliva samples from 5,000 kids were scanned and compared to responses using the Toronto Obsessive-Compulsive Scale. The team identified that those with a genetic variant in the gene PTPRD had a greater risk for obsessive-compulsive traits. Findings published in Translational Psychiatry. ....

Paul Arnold , Christie Burton , Russell Schachar , Jennifer Crosbie , Neurosciences Mental Health , Cumming School Of Medicine , Mathison Centre For Mental Health Research Education , University Of Calgary , Ontario Science Centre , Sick Children , Mathison Centre , Mental Health Research , Cumming School , Toronto Obsessive Compulsive Scale , Mental Health , Clinical Psychologist , Medicine Health , Coping Phobias , Stress Anxiety , பால் அர்னால்ட் , கிறிஸ்டி பர்டன் , ஜெனிபர் க்ராஸ்பி , நரம்பியல் மன ஆரோக்கியம் , கம்மிங் பள்ளி ஆஃப் மருந்து , மததிசோன் மையம் க்கு மன ஆரோக்கியம் ஆராய்ச்சி கல்வி , பல்கலைக்கழகம் ஆஃப் கல்கரி ,

Astrocyte cells in the fruit fly brain are an on-off switch that controls when neurons can change and grow

Adaptable neurons are tied to learning and memory but also to neurological disorders. By studying fruit flies, researchers found a mechanism that controls neuroplasticity. ....

Sarah Degenova Ackerman , Research Brief , Alzheimer 39s Disease , Brain Cells , Fruit Flies , New Research , Quick Reads , ஆராய்ச்சி சுருக்கமான , மன இறுக்கம் , மூளை செல்கள் , பழம் ஈக்கள் , புதியது ஆராய்ச்சி , விரைவான ரீட்ஸ் ,

USC Stem Cell study reveals neural stem cells age rapidly

Credit: Albina Ibrayeva/Bonaguidi Lab
In a new study published in
Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, PhD, demonstrates that neural stem cells - the stem cells of the nervous system - age rapidly.
There is chronological aging, and there is biological aging, and they are not the same thing, said Bonaguidi, an Assistant Professor of Stem Cell Biology and Regenerative Medicine, Gerontology and Biomedical Engineering at the Keck School of Medicine of USC. We re interested in the biological aging of neural stem cells, which are particularly vulnerable to the ravages of time. This has implications for the normal cognitive decline that most of us experience as we grow older, as well as for dementia, Alzheimer s disease, epilepsy and brain injury. ....

United States , United Kingdom , Los Angeles , Daniel Aaron , Heechul Jun , Galen Resler , Mi Hyeon Jang , Elbert Pu , Benjamind Simons , Naibo Zhang , Albina Ibrayeva , David Jorg , Axel Hidalgo , Congrui Lin , Michael Bonaguidi , Stem Cell Research , National Institutes Of Health , Deliab Baxter Foundation , Mayo Clinic College Of Medicine , Keck School Of Medicine , Bonaguidi Lab , University Of Cambridge , Provost Research Enhancement Fellowship , Royal Societyep Abraham Professorship , Edythe Broad Foundation , Edythe Broad Center ,