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New study gives the most detailed look yet at the neuroscience of placebo effects

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IMAGE: fMRI activity during pain is reduced in the areas shown in blue. Many of these are involved in constructing the experience of pain, including the feeling of suffering, and motivating.
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Credit: Image provided by M.Zunhammer et al.
A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual s mindset, not to the drug itself. Understanding the neural mechanisms driving this placebo effect has been a longstanding question. A meta-analysis published in
Nature Communications finds that placebo treatments to reduce pain, known as placebo analgesia, reduce pain-related activity in multiple areas of the brain. ....

Ulrike Bingel , Dianal Taylor , Matthias Zunhammer , Nature Communications , Behavioral Sciences , Affective Neuroscience Lab At Dartmouth , Placebo Neuroimaging Consortium , University Hospital Essen , Tor Wager , Distinguished Professor , Affective Neuroscience Lab , Treatment Expectation , Medicine Health , Health Care Systems Services , Health Professionals , Internal Medicine , Social Behavioral Science , Mental Health , இயற்கை தகவல்தொடர்புகள் , நடத்தை அறிவியல் , உவ்ர்ச்சி சார்ந்த நரம்பியல் ஆய்வகம் இல் டார்ட்மவுத் , மருந்துப்போலி நியூரோஇமேஜிங் கூட்டமைப்பு , பல்கலைக்கழகம் மருத்துவமனை எஸெந் , டோர் பந்தயம் , புகழ்பெற்ற ப்ரொஃபெஸர் , உவ்ர்ச்சி சார்ந்த நரம்பியல் ஆய்வகம் ,

'Will my face stay like this forever?': How it feels to have Bell's palsy

Emma was on holiday with her family two days before she developed Bell s palsy
Have you heard of Bell’s palsy? I certainly hadn’t, until it paralysed one side of my face.
My eldest son and I were in the garden in our pyjamas, picking blackberries. It was a lovely summer’s morning and we’d just come home from a family holiday in France.
My husband, Will, was taking photos of us but I couldn’t smile properly. It was the strangest feeling. I ignored it, as busy mums of small children often do with things concerning themselves, but the right side of my face felt heavier and when I looked in the mirror, my eyebrow had dropped and my mouth was lopsided. ....

United States , United Kingdom , City Of , Gigi Taguri , Angelina Jolie , Brad Pitt , Charles Bell , George Clooney , Charles Nduka , Centre For Appearance Research , University Of West England , University College Hospital , Speech Test , Facial Palsy Awareness Week , North East , Vanity Fair , Facial Palsy United Kingdom , Appearance Research , West England , Health And Fitness , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , ஏஞ்சலினா ஜோலி , பிராட் குழி , சார்லஸ் மணி ,

Potential drug for Alzheimer's disease prevention found safe and effective in animals

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IMAGE: Compared with a control (left), treatment with the novel GSM (right) reduces the number of amyloid plaques (green) and proinflammatory cells called microglia (magenta) in the brains of mice carrying.
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Credit: ©2021 Rynearson et al. Originally published in
Journal of Experimental Medicine. https://doi.org/10.1084/jem.20202560
Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer s disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain. The study, which will be published March 2 in the
JEM), demonstrates that the drug is safe and effective in rodents and monkeys, paving the way for future clinical trials in humans. ....

New York , United States , San Diego , Rockefeller University , University Of California San Diego , Stevenl Wagner , Rudolphe Tanzi , Department Of Neurosciences , Uc San Diego School Of Medicine , California San Diego School , Massachusetts General Hospital , Experimental Medicine , Diego School , Massachusetts General , Rockefeller University Press , Cell Biology , Medicine Health , Alzheimers Disease , Pharmaceutical Science , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , ராக்ஃபெல்லர் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா சான் டியாகோ , துறை ஆஃப் நரம்பியல் , அக் சான் டியாகோ பள்ளி ஆஃப் மருந்து ,

'Fish DJ' tackles fish hearing

A Fish DJ at The University of Queensland has used her knowledge of cool beats to understand brain networks and hearing in baby fish. ....

Bethan Scott , Rebecca Poulsen , Queensland Brain Institute , University Of Queensland , Associate Professor Ethan Scott , Cant Touch , Medicine Health , Mental Health , ஈதன் ஸ்காட் , ரிபேக்க போஉல்சென் , குயின்ஸ்லாந்து மூளை நிறுவனம் , பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்து , இணை ப்ரொஃபெஸர் ஈதன் ஸ்காட் , முடியாது தொடு , மருந்து ஆரோக்கியம் , மன ஆரோக்கியம் ,

Novel drug prevents amyloid plaques, a hallmark of Alzheimer's disease

Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques. ....

San Diego , United States , New Hampshire , University Of California San Diego , Douglas Galasko , Kevind Rynearson , Brian Spencer , Jazmin Florio , Carlos Arias , Roberta Rissman , Gopal Thinakaran , Yuhuan Xie , Graham Johnson , Jiunnh Lin , Michael Mante , Mariko Sawa , Olga Prikhodko , Rudolph Tanzi , Moorthi Ponnusamy , Yann Becker , Bahar Salehi , Stevenk Duddy , Williamc Mobley , Stevenl Wagner , Phuong Nguyen , Centers For Disease ,