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Global scarcity of novel antibiotics drives the emergence and spread of antimicrobial resistance


Global scarcity of novel antibiotics drives the emergence and spread of antimicrobial resistance
The world is still failing to develop desperately needed antibacterial treatments, despite growing awareness of the urgent threat of antibiotic resistance, according to report by the World Health Organization. WHO reveals that none of the 43 antibiotics that are currently in clinical development sufficiently address the problem of drug resistance in the world s most dangerous bacteria.
The persistent failure to develop, manufacture, and distribute effective new antibiotics is further fueling the impact of antimicrobial resistance (AMR) and threatens our ability to successfully treat bacterial infections.
Dr. Hanan Balkhy, Assistant Director General on AMR, WHO ....

Hanan Balkhy , Emily Henderson , Haileyesus Getahun , Action Fund , World Health Organization , Global Antibiotic Rd Partnership , European Investment Bank , World Health , Assistant Director General , Antibacterial Pipeline Report , Priority Pathogens List , Neglected Diseases , Antibiotic Resistance , Antimicrobial Resistance , எமிலி ஹென்டர்சன் , நடவடிக்கை நிதி , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , உலகளாவிய நுண்ணுயிர்க்கொல்லி ர்ட் கூட்டு , ஐரோப்பிய முதலீடு வங்கி , உலகம் ஆரோக்கியம் , உதவியாளர் இயக்குனர் ஜநரல் , புறக்கணிக்கப்பட்டது நோய்கள் ,

BGU researchers identify probiotic yogurt-based drug candidates

A crisis bigger than Covid: The new war on antibiotic resistance


A crisis bigger than Covid: The new war on antibiotic resistance
5 Apr, 2021 09:45 PM
8 minutes to read
No new class of antibiotics has been brought to market for decades. Photo / Sharon McCutcheon, Unsplash
No new class of antibiotics has been brought to market for decades. Photo / Sharon McCutcheon, Unsplash
Daily Telegraph UK
By: Harry de Quetteville
Isabelle Carnell-Holdaway was only 15 when, in 2017, the cystic fibrosis she had endured all her life forced her to have a double lung transplant.
CF patients depend on antibiotics every day to keep at bay infections that scar their lung tissue. After her transplant, with her immune system suppressed to prevent rejection of the new organs, Isabelle was even more reliant on the drugs. ....

United States , United Kingdom , City Of , Matt Hancock , Tim Walsh , Jeeva Sankar , Isabelle Carnell Holdaway , Alexander Fleming , David Livermore , Development Authority , Development Partnership , Oxford Institute , Global Antibiotic Research , Birmingham University , America Biomedical Advanced Research , India Institute Of Medical Sciences , Oxford University , Great Ormond Street Hospital , All India Institute , Jordi Vila , Health Secretary Matt Hancock , Lordo Neill , Laura Piddock , Medical Microbiology , Biomedical Advanced Research , Pew Trust ,

Total Knee Replacement Poses High Risk of Acute Kidney Injury


Total Knee Replacement Poses High Risk of Acute Kidney Injury
by Karishma Abhishek on 
April 4, 2021 at 11:04 AM
The Journal of Bone & Joint Surgery, published in the
Lippincott portfolio in partnership with
Wolters Kluwer.
In the two-stage exchange arthroplasty, the
knee implant is removed to enable treatment of the infection followed by placement of antibiotic-loaded bone cement (ALBC) spacers. The spacers deliver high doses of antibiotics directly and continuously to the site of the infection. Upon the eradication of the infection, another operation is performed to place new knee prosthesis.
‘High risk of acute kidney injury is estimated in patients undergoing treatment for infected total knee replacement. This emphasizes the importance of screening to identify patients with possible decreases in kidney function before two-stage exchange arthroplasty. Also, the risk of AKI related to pre-existing CKD and toxicit ....

Acute Kidney Injury , Total Knee Replacement , Chronic Kidney Disease , எடுப்போசை கிட்நீ காயம் , மொத்தம் முழங்கால் மாற்று , நாள்பட்ட கிட்நீ நோய் ,