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but it is a tough challenge. >> when you're dealing with something as profoundly basic as the organism's desire to consume food, it's not all that likely that we're going to be able to find one drug that is able to go to exactly the appetite center and zap it, and not do anything else. >> the risk greatly exceeds the benefit. >> reporter: the fda panel's advice, to pull the diet drug off the market or restrict it, is a huge disappointment to janet gebhart. she says meridia helped her on a program to lose a lot of weight. >> i understand people have concerned about the health risks, but at the same time, there are lots of drugs that people have concerns about. >> reporter: lately, attention has turned to two newly approved devices which use lasers or freeze fat cells to contour the body at a cost up to $3,000. another approach but no magic bullet for weight loss. robert bazell, nbc news, new