The first confirmed case of SARS-CoV-2 infection in the United States was reported one year ago today. A year later, 24 million Americans have been infected and 400,000 have died (worldwide, the sums are 95 million and two million, respectively). This pandemic doesn’t give a damn about partisan politics, presidential or otherwise. It methodically, cruelly rolls on as vaccines slowly, tentatively roll out—and as one administration rolls into another. The new President has promised a herculean and coordinated effort to vaccinate the population, while leaders around the world pledge the same for their countries. The first 100 days of the Joe Biden presidency will be as closely watched as Franklin Delano Roosevelt’s first 100 days in 1933, in the throes of the Great Depression.