With Vaccine Delay, Biden Warns of Uncertain End to Pandemic On a visit to a vaccine manufacturing plant in Michigan, President Biden said the nation could be “approaching normalcy” by the end of the year, but said new virus variants could slow progress. President Joseph R. Biden Jr. after touring the Pfizer manufacturing site in Kalamazoo, Mich.Credit...Doug Mills/The New York Times Published Feb. 19, 2021Updated March 8, 2021 WASHINGTON — President Biden, on a visit to Pfizer’s coronavirus vaccine plant in Kalamazoo, Mich., said on Friday that the nation could be “approaching normalcy” by the end of the year, but cautioned that new virus variants and potential vaccine production problems could slow progress.