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Coloring tumors reveals their bad influence

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IMAGE: Confocal micrographs of mouse small intestine with the Red2Onco technology. With Red2Onco, the oncogenic mutant clones (Red clones), and normal or wild-type clones (Yellow or Cyan clones) can be labeled.
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Credit: ©Yum/IMBA
Studies on cancer are limited by the threshold at which cellular transformations become clinically detectable. However, the very initial phase on the way to malignancy is histologically invisible, as the process originates from one single cell. In this early phase, a so-called seeding cell acquires an initial pro-cancerous mutation, also known as the first oncogenic hit , while being completely surrounded by normal tissue. To overcome the detection barrier, a team of researchers around IMBA group leader Bon-Kyoung Koo and University of Cambridge group leader Professor Benjamin D. Simons developed a laboratory system to dissect the pre-cancerous steps that remained under the radar up until present. ....

United Kingdom , Benjamin Simons , Bon Kyoung Koo , Benjamind Simons , Seungmin Han , University Of Cambridge , Austrian Federal Ministry Of Science , Gurdon Institute , Institute Of Molecular Biotechnology , Austrian Academy Of Sciences , Professor Benjamin , Min Kyu Yum , Bone Morphogenic Protein , Min Kyu , Molecular Biotechnology , Vienna Biocenter , Austrian Academy , Austrian Federal Ministry , Biomedical Environmental Chemical Engineering , Cell Biology , Developmental Reproductive Biology , Molecular Biology , ஒன்றுபட்டது கிஂக்டம் , பெஞ்சமின் சிமன்கள் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , ஆஸ்திரேலிய கூட்டாட்சியின் அமைச்சகம் ஆஃப் அறிவியல் ,

Oncotarget: Lung squamous cell carcinoma tumors reveal therapeutic alterations

Lung cancer is the leading cause of cancer-related deaths across the globe with more than 1.7 million deaths annually. ....

Amit Dutt , Kumar Prabhash , Dutt Prabhash Research Team , Prabhash Research Team , Oncotargetresearch Output , Science Math , Medicine Health , Breast Cancer , Prostate Cancer , Policy Ethics , அமித் தத் , குமார் பிரபாஷ் , ஒலி கிளவுட் , பிரபாஷ் ஆராய்ச்சி அணி ,

MDI Biological Laboratory scientist identifies signaling underlying regeneration

The mystery of why salamanders can regenerate a lost limb, but adult mammals cannot has fascinated observers for thousands of years. Now, a team of scientists led by James Godwin, Ph.D., of the MDI Biological Laboratory in Bar Harbor, Maine, has come a step closer to unraveling that mystery with the discovery of differences in molecular signaling that promote regeneration in the axolotl, a highly regenerative salamander, while blocking it in the adult mouse. ....

United States , Bar Harbor , Hermann Haller , Sergej Nowoshilow , James Godwin , Nadia Rosenthal , Bryan Dubuque , Katyae Chan , Sciences Of The National Institutes Health , Research Institute Of Molecular Pathology , Australian Regenerative Medicine Institute , Laboratory In Bar Harbor , Jackson Laboratory , National Institute , Institutional Development Award Ide , Salamander Response , Research Institute , Molecular Pathology , Institutional Development Award , General Medical Sciences , National Institutes , State Government , Cell Biology , Developmental Reproductive Biology , Molecular Biology , Pharmaceutical Science ,

Gender Equality Comes for Crash Test Dummies – RedState

Yes tests are still a thing. ....

United States , District Of Columbia , Rex Chapman , Eleanor Holmes Norton , Traffic Safety Administration , National Highway Traffic Safety Administration , Federal Highway Administration , Hispanic White , Hispanic Black , Consumer Reports , Save Women , Enters For Disease Control And Prevention , Consumer Reports , District Of Columbia , Eleanor Holmes Norton , Gender Identity , House Of Representatives , Crash Test Dummy , Car Accidents , Ubcommittee On Highways And Transit , National Highway Traffic Safety Administration , ஒன்றுபட்டது மாநிலங்களில் , மாவட்டம் ஆஃப் கொலம்பியா , ரெக்ஸ் சாப்மேன் , எலினோர் ஹோம்ஸ் நார்டன் , ஹிஸ்பானிக் வெள்ளை ,

Study offers insights for communicating about wildlife, zoonotic disease amid COVID-19

A new study from North Carolina State University found that certain types of messages could influence how people perceive information about the spread of diseases from wildlife to humans. ....

United States , Nils Peterson , Stevenb Jackson , Kathrynt Stevenson , M Nils Peterson , Justinm Beall , Lincoln Larson , Wyliea Carr , Justin Beall , Williamr Casola , Erin Seekamp , Lincolnr Larson , National Climate Adaptation Science Center , World Health Organization , Carolina State University , North Carolina State University , Climate Adaptation Science , Nature Science , Ecology Environment , Environmental Health , ஒன்றுபட்டது மாநிலங்களில் , நில்ஸ் பீட்டர்சன் , மீ நில்ஸ் பீட்டர்சன் , லிங்கன் லார்சன் , ஜஸ்டின் பீல் , தேசிய காலநிலை வேறுபடுத்தி அமைத்தல் அறிவியல் மையம் ,