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Study pinpoints potential transmission advantage of SARS-CoV-2 variant B.1.1.7

Researchers in the UK have shown that the increased transmissibility of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage B.1.1.7 that emerged in the UK during the coronavirus disease 2019 (COVID-19) pandemic does not appear to be the result of increased viral replication or immune escape. ....

United Kingdom , City Of , Wendy Barclay , Sally Robertson , Imperial College London , Royal Brompton , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , In Vitro , In Vivo , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , வெண்டி பார்க்லே , சாலி ராபர்ட்சன் , ஏகாதிபத்தியம் கல்லூரி லண்டன் , அரச ப்ரொம்ப்டன் , கொரோனா வைரஸ் , இல் விட்ரோ , இல் விவோ , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Immunologists map unknown biological machinery to produce memory T cells

Immunologists map unknown biological machinery to produce memory T cells
Immunologists at St. Jude Children s Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses, and tumor cells.
The findings have multiple implications for how the adaptive immune system responds to infections to generate such memory T cells. The experiments revealed mechanisms that inhibit the development of the long-lived memory T cells that continually renew to protect the body over time.
Blocking these inhibitory mechanisms with pharmacological or genetic approaches could boost protective immunity against infection and cancers.
The researchers also discovered a subtype of memory T cells that they named terminal effector prime cells. Mapping the pathway that controls these cells raises the possibility of manipulating this pathway to enhance the ability of the immune system to kill microbes and cancer c ....

Hongbo Chi , Peipei Zhou , Hongling Huang , Emily Henderson , Jude Children Research Hospital , Department Of Immunology , Jude Children , Research Hospital , Immune System , பேய்ப்பே ஜூ , எமிலி ஹென்டர்சன் , ஜூட் குழந்தைகள் ஆராய்ச்சி மருத்துவமனை , துறை ஆஃப் நோயெதிர்ப்பு , ஜூட் குழந்தைகள் , ஆராய்ச்சி மருத்துவமனை , நோய் எதிர்ப்பு சக்தி அமைப்பு ,

Researchers identify cells responsible for maintenance and regeneration of liver

Researchers identify cells responsible for maintenance and regeneration of liver
While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery.
Now, research from the Children s Medical Center Research Institute at UT Southwestern (CRI) has identified the cells responsible for liver maintenance and regeneration while also pinpointing where they reside in the liver.
These findings, reported today in
Science, could help scientists answer important questions about liver maintenance, liver damage (such as from fatty liver or alcoholic liver disease), and liver cancer.
The liver performs vital functions, including chemical detoxification, blood protein production, bile excretion, and regulation of energy metabolism. Structurally, the liver is comprised of tissue units called lobules that, when cross-sectioned, resemble honeycombs. ....

Zhao Zhu , Emily Henderson , Children Medical Center Research Institute , Ut Southwestern Medical Center , Medical Center Research Institute , Study Lead Author , Associate Professor , Fatty Liver , Liver Cancer , Liver Disease , Stem Cells , ஹ்ம் ஜு , எமிலி ஹென்டர்சன் , குழந்தைகள் மருத்துவ மையம் ஆராய்ச்சி நிறுவனம் , உட் தென்மேற்கு மருத்துவ மையம் , மருத்துவ மையம் ஆராய்ச்சி நிறுவனம் , படிப்பு வழி நடத்து நூலாசிரியர் , இணை ப்ரொஃபெஸர் , கொழுப்பு கல்லீரல் , கல்லீரல் புற்றுநோய் , கல்லீரல் நோய் , வளர்சிதை மாற்றம் , தண்டு செல்கள் ,

Welcome To IANS Live - LatestNews - Researchers reveal not all 'good' cholesterol is healthy

The findings indicate that people with large high-density lipoprotein (HDL) particles have an increased risk of myocardial infarction, while only small HDL particles are actually associated with decreased risk. ....

City Of , United Kingdom , India Private , News Service , All Rights , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , இந்தியா ப்ரைவேட் , செய்தி சேவை , அனைத்தும் உரிமைகள் ,

Catalent to Acquire Delphi Genetics

Cédric Szpirer, Founder and Executive Director of Delphi Genetics, added, “The complementary activities and adjacent technologies will provide our customers, our employees, and ultimately patients around the world with a solid foundation for new therapeutic solutions in the cell and gene therapy domain.”
Upon completion, all of Delphi’s highly skilled team, including R&D and genetic engineering scientists and technicians, regulatory specialists, and other associated roles will transfer to Catalent’s Cell and Gene Therapy business.
This acquisition fast-tracks Catalent’s U.S. expansion of plasmid capabilities at its Rockville facility. Since acquiring the site in 2019, Catalent has invested to upgrade the facility with the addition of dedicated single-use microbial capacity for plasmid DNA production. Process and analytical development for plasmid DNA are also available on site, and the facility will also offer research- and CGMP-grade plasmids to support its vir ....

United States , New Jersey , Waals Gewest , Bruxelles Capitale , Manja Boerman , European Center , Adelphi Genetics , Catalent Cell , Executive Director , Gene Therapy , Consumer Health , Viral Vector , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஜெர்சி , ப்ரூக்ஸெல்ஸ் தலைநகரம் , ஐரோப்பிய மையம் , டெல்பி ஜெநெடிக்ஸ் , நிர்வாகி இயக்குனர் , கீந் சிகிச்சை , நுகர்வோர் ஆரோக்கியம் , வைரஸ் திசையன் ,