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Glomerulonephritis Patients Face High Risk of Recurrence After Kidney Transplant

A single-center assessment showed patients with glomerulonephritis may face a heightened risk of primary disease recurrence up to 1 year after transplant.

Warsaw , L67- , Poland , Weermeijer-unsplash , Monika-wieliczko , University-of-warsaw , Robina-weermeijer , Medical-university , Glomerulonephritis-after-kidney-transplantation , One-center , Berger-disease , Treasure-island

The making of Good Queen Bess

In the course of British history there have been few royals with a childhood as traumatic as that of Elizabeth I. She endured the torment of her mother Anne Boleyn’s execution, her father’s death, the comings and goings of four stepmothers, sexual abuse from a stepfather (who was executed soon after), the death of a

United-kingdom , British , Britain , Nicola-tallis , Margaret-beaufort , Lettice-knollys , Anne-boleyn , Lady-jane-grey , Lady-elizabeth , Lady-princess , Beheading

Patients With Stable Lupus May Be Safely Weaned Off MMF

Rates of significant disease reactivation were similar more than 1 year after randomization for patients assigned to mycophenolate mofetil (MMF) withdrawal or MMF maintenance.

France , Massachusetts , United-states , Boston , Elizaf-chakravarty , Karenh-costenbader , Laurent-chiche , Lupus-program-at-brigham , American-college-of-rheumatology , Marseille-university-in , University-of-oklahoma-college-medicine , Harvard-medical-school

Urine Test Biomarker Allows Diagnosis Without Kidney Biopsy

Patients with acute tubulointerstitial nephritis show high levels of the protein CXCL9 in urine, potentially allowing for diagnosis without the need for a kidney biopsy.

Baltimore , Maryland , United-states , Chirag-parikh , Yale-school-of-medicine , Division-of-nephrology-at-johns-hopkins-medicine , Johns-hopkins-medicine , Yale-school , Renal-failure , Enal-insufficiency , Idney-insufficiency , Idney-failure

Lupus Nephritis: Hopes, Questions Arise for Baricitinib

Results from a small, independently funded, double-blind, active-comparator trial suggest that baricitinib could be beneficial in the treatment of lupus nephritis.

Italy , United-states , Monash , South-australia , Australia , Egypt , Melbourne , Victoria , Milan , Lombardia , Ericf-morand , Manal-hassanien

Early Remission in Lupus Nephritis May Not Bar Advanced CKD

Patients with lupus nephritis who achieve complete remission within 1 year of starting treatment can still develop advanced chronic kidney disease within a few years.

South-korea , Toronto , Ontario , Canada , Melbourne , Victoria , Australia , Seoul , Soult-ukpyolsi , Bristol-myers-squibb , Eli-lilly , Dafna-gladman

New Tool Better Estimates CV Risk in People With Lupus

A tool to estimate cardiovascular risk in systemic lupus erythematosus incorporates disease-specific variables.

California , United-states , Los-angeles , Eli-lilly , Maureen-mcmahon , University-of-california , Glaxosmithkline , Werfen-international , Medscape-professional-network , Lupus-clinical-trials-network , Astrazeneca , Aurinia-pharmaceuticals

FDA announces drug trial information for new lupus and chronic heart failure medications

FDA announces drug trial information for new lupus and chronic heart failure medications
Food and Drug Administration (generic). (Source: CNN)
By KOLD News 13 Staff | February 10, 2021 at 3:29 PM MST - Updated February 10 at 3:29 PM
TUCSON, Ariz. (KOLD News 13) - Today, the U.S. Food and Drug Adminstration announced the information for two new medications that recently underwent clinical trials.
The first is called
Lupkynis (loop kye’ nis) and is used to treat patients with active lupus [nephritis], an inflammation of the kidneys that is caused by a chronic auto-immune disease.
According to the FDA, patients who received the drug for one year acheived major reduction in kidney inflammation.

Drug-adminstration , Fda , Approve , Clinical , Trial , Information , Chronic , Health , Failure , Lupus , Nephritis

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes
A study by Mayo Clinic researchers published in
Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.
Immune checkpoint inhibitors have improved the prognosis for patients with a wide range of malignancies including melanoma, non-small cell lung cancer and renal cancer. In some patients, this enhanced immune response may target kidney tissue, leading to acute kidney inflammation known as interstitial nephritis."

Sandra-herrmann , Emily-henderson , Kidney-international , Mayo-clinic , Kidney-international-reports , Mayo-clinic-nephrologist , Cancer , Kidney , Acute-kidney-injury , Biopsy , Cell , Creatinine

Today In Johnson City History: Jan. 26

Jan. 26, 1888: The Comet reminded readers that there would be a total eclipse of the moon the following Saturday night.

Washington , District-of-columbia , United-states , East-tennessee-state-university , Tennessee , Chattanooga , Jonesboro , Florida , Science-hill-high-school , Elizabethton , Johnson-city , Thada-cox