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This Frontline Therapy Is Better in Multiple Myeloma: Study

A study directly comparing real-world outcomes suggests patients with transplant-ineligible multiple myeloma do better with frontline triple therapy with daratumumab vs bortezomib.

United-states , Florida , American , Dorisk-hansen , American-society-of-hematology , National-comprehensive-cancer-network , Moffitt-cancer-center-research-institute-in-tampa , Moffitt-cancer-center , Research-institute , American-society , Multiple-myeloma

No Benefit to Salvage Transplant in R/R Multiple Myeloma

Long-term follow-up shows no progression-free or overall survival advantage among patients who received salvage transplant vs continuous lenalidomide plus dexamethasone.

Salt-lake-city , Utah , United-states , Heidelberg , Baden-wüberg , Germany , University-of-utah , German , American , Manni-mohyuddin , Marc-andrea-baertsch , University-hospital-heidelberg

Sickle Cell: Good Outcomes for Haploidentical Transplants

It is much easier to find eligible haploidentical donors — half-matched or partially matched — than eligible hematopoietic donors.

Minnesota , United-states , Vanderbilt-university , Tennessee , Mayo-clinic-in-rochester , American , Adetolaa-kassim , Lansky-karnofsky , Asmaa-ferdjallah , Blood-institute , Vanderbilt-university-medical-center , National-heart

Stem Cell Therapy Implant Shows Promise for Type 1 Diabetes

An experimental device containing millions of stem cells significantly reduced the need for insulin shots among people with type 1 diabetes.

Toronto , Ontario , Canada , Belgium , United-kingdom , Vancouver , British-columbia , United-states , American , British , David-thompson , Robert-gabbay

MRD Status Predicts Transplant Benefit in NPM1-Mutated AML

MRD-positive patients in first complete remission after induction therapy had a survival benefit after transplant; however, that benefit did not extend to MRD-negative patients after transplant.

Sydney , New-south-wales , Australia , London , City-of , United-kingdom , United-states , American , King-college-london , United-kingdom-national-cancer-research-institute , University-of-sydney

Hematology Is in the Brodsky Family's Blood

Talk about bloodlines: In the Brodsky family, the field of hematology tied father to son. Now, a grandson is heading into the "family business."

Atlantic-city , New-jersey , United-states , Pennsylvania , University-of-pennsylvania , Vietnam , Republic-of , San-diego , California , Delaware , American , Max-brodsky

FDA OKs Two Gene-Editing Therapies for Sickle Cell Disease

The approval for the two gene-editing treatments, called exa-cel and lovo-cel, could help thousands with the blood disorder.

United-states , American , Roberta-brodsky , Franco-locatelli , Nicole-verdun , Johns-hopkins-university-school-of-medicine , Sapienza-university-of-rome , Vertex-pharmaceuticals , Drug-administration , American-society-of-hematology , Crispr-therapeutics , Johns-hopkins-university-school

Time to Stop Routine Maintenance Therapy in Myeloma?

Physicians may need to rethink maintenance with lenalidomide (Revlimid and generics) for multiple myeloma.

United-states , New-york , Memorial-sloan-kettering-cancer-center , Boston , Massachusetts , Spain , Spanish , Nikhil-munshi , Sergio-giralt , Benjamin-derman , Shaji-kumar , International-myeloma-working-group

Time to Add aHSCT to Standard Care in RRMS?

73% of patients with relapsing remitting multiple sclerosis were disease free 5 years after aHSCT treatment, and more than half reported improved disability.

Sweden , Stockholm , Uppsala , Uppsala-lan , Dalarna , Kopparberg , Swedish , Joachim-burman , Clinical-research-dalarna , Swedish-research-council , Marcus-wallenberg-foundation , Regional-research-council

Israeli Scientists Create Model of Human Embryo Without Eggs or Sperm

Scientists in Israel have created a model of a human embryo from stem cells in the laboratory, without using sperm, eggs or a womb, offering a unique glimpse into the early stages of embryonic development.

Boston , Massachusetts , United-states , Israel , Cambridge , Cambridgeshire , United-kingdom , Rehovot , Hamerkaz , Israeli , Mark-heinrich , Jacob-hanna