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Scientists identify genomic signatures of long-term survival in luminal breast cancer patients

Scientists identify genomic signatures of long-term survival in luminal breast cancer patients
Researchers at NUI Galway have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival. The NUI Galway team analyzed the genomes of breast cancer patients to look for associations with survival rates using advanced statistical techniques.
Carried out by Lydia King during her studies in NUI Galway s MSc in Biomedical Genomics programme, the research has been published in the international journal
PLOS ONE.
Early detection by national screening programmes and timely treatment for patients diagnosed with luminal types of breast cancer have resulted in excellent prognoses with survival rates of over 80% within five years of treatment. The challenge of long-term survival however is not as well understood and studies have shown that more than half of all recurrences for luminal breast cancers take ....

United Kingdom , Emma Holian , Andrew Flaus , Lydia King , Emily Henderson , Cambridge University , Molecular Taxonomy Of Breast Cancer International Consortium , School Of Natural Sciences , Galway School Of Mathematics , Science Foundation Ireland , Biomedical Genomics , Molecular Taxonomy , Breast Cancer International Consortium , Natural Sciences , Aaron Golden Senior Author , Programme Director , Research Training , Genomics Data Science , Cancer Treatment , Breast Cancer , ஒன்றுபட்டது கிஂக்டம் , எம்மா ஹோலியன் , லிடியா கிங் , எமிலி ஹென்டர்சன் , கேம்பிரிட்ஜ் பல்கலைக்கழகம் , பள்ளி ஆஃப் இயற்கை அறிவியல் ,

Researchers to create computational models to improve treatments for ovarian cancer

Researchers to create computational models to improve treatments for ovarian cancer
The 5-year research project involves 14 organizations in seven EU countries and is funded by €15 M from the EU.
The Genome Data Science lab, led by ICREA researcher Fran Supek, will analyze the evolution of ovarian tumors to develop computational models for predicting treatment resistance.
The EU has granted €15 M to fund a 5-year project that seeks to improve personalized treatments for ovarian cancer. The international DECIDER project involves partners from 14 organizations in seven EU countries.
In Europe, over 40000 women die of ovarian cancer every year. In addition to surgery, most patients are treated with platinum-based chemotherapy. Unfortunately, the effect of the chemotherapy often decreases with treatment cycles, and few effective treatments are currently available for patients who develop resistance to platinum-based drugs. ....

Comunidad Autonoma De Cataluna , Eteläuomen Läi , Sampsa Hautaniemi , Fran Supek , Emily Henderson , University Of Helsinki , Genome Data Science , Ovarian Cancer , Research Project , காமுனிடட தன்னாட்சி டி கடலுள் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஹெல்சின்கி , மரபணு தகவல்கள் அறிவியல் , ஓவாயரியந் புற்றுநோய் , ஆராய்ச்சி ப்ராஜெக்ட் , அறுவை சிகிச்சை ,

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer
A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.
Lung cancer researchers and clinicians have sought methods to improve chemotherapy s modest 5% overall survival rate for patients with NSCLC. Dr. Silvia Novello, professor of medical oncology at the University of Torino at San Luigi Gonzaga Hospital, Orbassano, Italy, and a large group of European researchers evaluated the predictive utility of the mRNA expression levels of molecular markers, mRNA expression levels of molecular markers, excision repair cross-complementing group ERC ....

Silvia Novello , Tetsuya Mitsudomi , Emily Henderson , University Of Torino , International Association , Lung Cancer World Conference , San Luigi Gonzaga Hospital , Medical Oncology , Lung Cancer , Non Small Cell Lung Cancer , Small Cell Lung Cancer , சில்வியா நாவல் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் டொரினோ , சர்வதேச சங்கம் , நுரையீரல் புற்றுநோய் உலகம் மாநாடு , சான் லூயிஜி கந்ஸாய மருத்துவமனை , மருத்துவ புற்றுநோயியல் , நுரையீரல் புற்றுநோய் , அல்லாத சிறிய செல் நுரையீரல் புற்றுநோய் , சிறிய செல் நுரையீரல் புற்றுநோய் , அறுவை சிகிச்சை ,

Experts predict 125,000 fewer COVID deaths if 50% of U.S. population initiate vaccination by March 1

A new report combining forecasting and expert prediction data, predicts that 125,000 lives could be saved by the end of 2021 if 50% or more of the U.S. population initiated COVID vaccination by March 1, 2021. ....

United Kingdom , Thomas Mcandrew , Emily Henderson , Lehigh University College Of Health , Lehigh University , Genomic Sequencing , ஒன்றுபட்டது கிஂக்டம் , தாமஸ் அம்கெஂட்ர்யூ , எமிலி ஹென்டர்சன் , லேஹி பல்கலைக்கழகம் கல்லூரி ஆஃப் ஆரோக்கியம் , லேஹி பல்கலைக்கழகம் ,

Researchers release first Japanese reference genome

The Japanese now have their own reference genome thanks to researchers at Tohoku University who completed and released the first Japanese reference genome (JG1). ....

Japan General , Gen Tamiya , Jun Takayama , Emily Henderson , Miyagi Cancer Research Institute , Tohoku University Medical Megabank Organization Tommo , Research Center , Japanese Reference Genome Assembly , Tohoku University School Of Medicine , Nature Communications On , School Of Information Sciences , Tohoku University , Study Co , Nature Communications , Study Co Author , Human Genome Project , Tohoku Medical Megabank Organization , Advanced Research Center , Next Generation Medicine , Tohoku University School , Information Sciences , ஜப்பான் ஜநரல் , கேன் தமியா , ஜூன் தக்காயமா , எமிலி ஹென்டர்சன் , மியையேஜை புற்றுநோய் ஆராய்ச்சி நிறுவனம் ,