abreva can get you back to being you in just 2 and a half days. be kinder to yourself and tougher on your cold sores. ...little things... ...can become your big moment. that's why there's otezla. otezla is not a cream. it's a pill that treats plaque psoriasis differently. with otezla, 75% clearer skin is achievable. don't use if you're allergic to otezla. it may cause severe diarrhea, nausea or vomiting. otezla is associated with an increased risk of depression.